Peptidases • Lichtheimia hyalospora v1.0
Annotations/GenomesLichy1Mucci2Phybl2Rhior3Umbra1TotalAnnotation Description
Merops
3113042842902721,461
2524283322132Water nucleophile; water bound by two Asp from monomer or dimer; all endopeptidases, from eukaryote organisms, viruses or virus-like organisms
3444318Water nucleophile; water bound by two Asp; all membrane-bound endopeptidases known only from eubacteria with active site on cytoplasmic side of cell membrane.
3535292824151Cysteine nucleophile; catalytic residues in the order Cys, His, Asn (or Asp) in sequence
5674224Cysteine nucleophile; catalytic residues in the order His, Cys in sequence
12328Cysteine nucleophile; catalytic residues in the order His, Glu (or Asp), Cys in sequence
112Cysteine nucleophile; catalytic residues in the order Glu, Cys, His in sequence
21126Cysteine nucleophile; catalytic residues in the order Cys, His, His in sequence
212218Cysteine nucleophile; catalytic residues in the order His, Cys in sequence
77613639Families of peptidase inhibitors not assigned to clans
11
112
11
11
2125
111216
321219
11114Families of metallopeptidases not assigned to clans
162317182296Water nucleophile; water bound by single zinc ion ligated to two His (within the motif HEXXH) and Glu, His or Asp
22Water nucleophile; water bound by single zinc ion ligated to His, Glu (within the motif HXXE) and His
11Water nucleophile; water bound by single zinc ion ligated to two His (within the motif HXXEH) and Glu
5434319Water nucleophile; water bound by two zinc ions ligated by Lys, Asp, Asp, Asp, Glu
111312131160Water nucleophile; water bound by two cobalt or manganese ions ligated by Asp, Asp, His, Glu, Glu
171115161776Water nucleophile; water bound by two zinc ions ligated by His (or Asp), Asp, Glu, Asp (or Glu), His
712941042Water nucleophile; water bound by two zinc ions ligated by His, His or Asp, Lys or Glu, His, His.
12115Water nucleophile; water bound by single zinc ion ligated to two His (within the motif HEXXH) and Asp; membrane proteins with intramembrane active site.
3656222Water nucleophile; water bound by single zinc ion ligated to two His and Asp (within the motif HSHP(X)9D)
211138Serine or cysteine nucleophile; catalytic residues in the order His, Asp, Ser (or Cys) in sequence; all endopeptidases
2023173218110Threonine, serine or cysteine nucleophile at the N-terminus of mature enzyme
5333317Serine or cysteine nucleophile; catalytic residues in the order Cys (or Ser), His, Glu in sequence.
11Serine or threonine nucleophile; N-terminal nucleophile
151019181072Serine nucleophile; catalytic residues in the order Asp, His, Ser in sequence in family S8, but family S53 differs
8267555371328Serine nucleophile; catalytic residues in the order Ser, Asp, His in sequence
3115Serine nucleophile; catalytic residues in the order Ser, Lys (within the motif SXXK) in sequence
4542318Serine nucleophile; catalytic residues in the order Ser, Lys (or His) in sequence
11Serine nucleophile; catalytic residues in the order Ser, Lys in sequence
1331210Serine nucleophile; catalytic residues in the order Ser, His, Asp in sequence
6774428Serine nucleophile; transmembrane protein with catalytic residues in the order Ser, His embedded in the membrane
112Families of peptidases of unknown catalytic mechanism not assigned to clans
111115
2324262317113
112
11