Peptidases • Polyplosphaeria fusca CBS 125425 v1.0
Annotations/GenomesAltbr1Amnli1CocheC5_3Cucbe1Didex1Dotsy1Karrh1Lenfl1Melpu1Plesi1Polfu1Pyrtr1Pyrtt1Settu1Spofi1Stano2Trepe1TotalAnnotation Description
Merops
2823773723283313024224284663534362973053242503434166,032
1224291623101721201220132616161322310Water nucleophile; water bound by two Asp from monomer or dimer; all endopeptidases, from eukaryote organisms, viruses or virus-like organisms
7712873865710889477123Water nucleophile; water bound by two Asp; all membrane-bound endopeptidases known only from eubacteria with active site on cytoplasmic side of cell membrane.
11Water nucleophile; water bound by two Asp
1929282828273231313228262422212528459Cysteine nucleophile; catalytic residues in the order Cys, His, Asn (or Asp) in sequence
3544434654444433569Cysteine nucleophile; catalytic residues in the order His, Cys in sequence
1111111211111121119Cysteine nucleophile; catalytic residues in the order His, Glu (or Asp), Cys in sequence
1212113322211122229Cysteine nucleophile; catalytic residues in the order Glu, Cys, His in sequence
11111117Cysteine nucleophile; catalytic residues in the order Cys, His, His in sequence
111111111111111116Cysteine nucleophile; catalytic residues in the order His, Cys in sequence
2152131244111311134Water nucleophile; water bound by Gln and Glu; all endopeptidases
4554565455555544581Families of peptidase inhibitors not assigned to clans
112
2111121111122111121
5633347644435435675
2564458884323534579Families of metallopeptidases not assigned to clans
1314111714171716272022141112101618269Water nucleophile; water bound by single zinc ion ligated to two His (within the motif HEXXH) and Glu, His or Asp
8677755644576757399Water nucleophile; water bound by single zinc ion ligated to His, Glu (within the motif HXXE) and His
1211112111221121223Water nucleophile; water bound by single zinc ion ligated to two His (within the motif HXXEH) and Glu
67667785777656676109Water nucleophile; water bound by two cobalt or manganese ions ligated by Asp, Asp, His, Glu, Glu
1626262425232926332626192022192225407Water nucleophile; water bound by two zinc ions ligated by His (or Asp), Asp, Glu, Asp (or Glu), His
12109810591312121512101371114182Water nucleophile; water bound by two zinc ions ligated by His, His or Asp, Lys or Glu, His, His.
3333433333333333352Water nucleophile; water bound by single zinc ion ligated to two His and Asp (within the motif HSHP(X)9D)
1113Water nucleophile; water bound by single zinc ion ligated to Asp, His and His.
4322214432122313241Serine or cysteine nucleophile; catalytic residues in the order His, Asp, Ser (or Cys) in sequence; all endopeptidases
2121202320202321222123192021192120355Threonine, serine or cysteine nucleophile at the N-terminus of mature enzyme
106987711107510899688138Serine or cysteine nucleophile; catalytic residues in the order Cys (or Ser), His, Glu in sequence.
11221119Cysteine nucleophile at the N-terminus of mature enzyme; catalytic residues in the order Cys, Thr, His
31111111111112118Serine or threonine nucleophile; N-terminal nucleophile
913169910191322161213141581211221Serine nucleophile; catalytic residues in the order Asp, His, Ser in sequence in family S8, but family S53 differs
871401321171161051601721771271839798114771331702,205Serine nucleophile; catalytic residues in the order Ser, Asp, His in sequence
6856881617257176624714162Serine nucleophile; catalytic residues in the order Ser, Lys (within the motif SXXK) in sequence
3532233323322323347Serine nucleophile; catalytic residues in the order Ser, Lys (or His) in sequence
2122121111122222126Serine nucleophile; catalytic residues in the order Ser, His, Asp in sequence
112Serine nucleophile; catalytic residues in the order Ser, Glu, His
2435544445534445570Serine nucleophile; transmembrane protein with catalytic residues in the order Ser, His embedded in the membrane
112Families of peptidases of unknown catalytic mechanism not assigned to clans
111111111110
151415101111141520912111012111016216
1121117
43115233221734