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Peptidases • Kockovaella imperatae NRRL Y-17943 v1.0
Annotations/GenomesCryne_H99_1Cryne_JEC21_1Diocr1Felpe1Fibin1Kocim1Sirint1Treen1Treme1TotalAnnotation Description
Merops
1571552832171812071962331491,778
661086967563Water nucleophile; water bound by two Asp from monomer or dimer; all endopeptidases, from eukaryote organisms, viruses or virus-like organisms
112Water nucleophile; water bound by two Asp; all membrane-bound endopeptidases known only from eubacteria with active site on periplasmic side of cell membrane.
11213221114Water nucleophile; water bound by two Asp; all membrane-bound endopeptidases known only from eubacteria with active site on cytoplasmic side of cell membrane.
141133151217161414146Cysteine nucleophile; catalytic residues in the order Cys, His, Asn (or Asp) in sequence
33745453438Cysteine nucleophile; catalytic residues in the order His, Cys in sequence
2316Cysteine nucleophile; catalytic residues in the order His, Glu (or Asp), Cys in sequence
213Cysteine nucleophile; catalytic residues in the order Glu, Cys, His in sequence
22Water nucleophile; water bound by Gln and Glu; all endopeptidases
22422222220Families of peptidase inhibitors not assigned to clans
11
22431121117
1222222215Families of metallopeptidases not assigned to clans
81017871399990Water nucleophile; water bound by single zinc ion ligated to two His (within the motif HEXXH) and Glu, His or Asp
1111111119Water nucleophile; water bound by single zinc ion ligated to His, Glu (within the motif HXXE) and His
11111117Water nucleophile; water bound by single zinc ion ligated to two His (within the motif HXXEH) and Glu
881287888875Water nucleophile; water bound by two cobalt or manganese ions ligated by Asp, Asp, His, Glu, Glu
13101018101213209115Water nucleophile; water bound by two zinc ions ligated by His (or Asp), Asp, Glu, Asp (or Glu), His
101115161312192010126Water nucleophile; water bound by two zinc ions ligated by His, His or Asp, Lys or Glu, His, His.
11111117Water nucleophile; water bound by single zinc ion ligated to two His (within the motif HEXXH) and Asp; membrane proteins with intramembrane active site.
55755555547Water nucleophile; water bound by single zinc ion ligated to two His and Asp (within the motif HSHP(X)9D)
1113Water nucleophile; water bound by single zinc ion ligated to Asp, His and His.
1113Asparagine nucleophile; catalytic residues in the order Asp, Asn in sequence; all self-processing endopeptidases
111115Serine or cysteine nucleophile; catalytic residues in the order His, Asp, Ser (or Cys) in sequence; all endopeptidases
171832222122252520202Threonine, serine or cysteine nucleophile at the N-terminus of mature enzyme
32523244328Serine or cysteine nucleophile; catalytic residues in the order Cys (or Ser), His, Glu in sequence.
111227Serine or threonine nucleophile; N-terminal nucleophile
11211411113Serine nucleophile; catalytic residues in the order Asp, His, Ser in sequence in family S8, but family S53 differs
404473655253487131477Serine nucleophile; catalytic residues in the order Ser, Asp, His in sequence
1686928150Serine nucleophile; catalytic residues in the order Ser, Lys (within the motif SXXK) in sequence
32433434329Serine nucleophile; catalytic residues in the order Ser, Lys (or His) in sequence
11112111110Serine nucleophile; catalytic residues in the order Ser, His, Asp in sequence
33434252430Serine nucleophile; transmembrane protein with catalytic residues in the order Ser, His embedded in the membrane
11114Families of peptidases of unknown catalytic mechanism not assigned to clans
1111111119
10101512111112119101
11
1113