Peptidases • Chytridiomycetes
Annotations/GenomesBatde5Blyhe1Caupr1Caupr_SCcombChyhya1Chylag1Chytri1Clapol1_1Clarep1_1Enthel1Fimjon1Gaesem1Gervar1Glopol1Gorhay1Hompol1Obemuc1Powhir1Rhihy1Spipu1Triarc1TotalAnnotation Description
Merops
314256152813623123553754822102322072403722631843302213602102175,735
10340772010273391484162710131552788411Water nucleophile; water bound by two Asp from monomer or dimer; all endopeptidases, from eukaryote organisms, viruses or virus-like organisms
6111110Water nucleophile; water bound by two Asp; all membrane-bound endopeptidases known only from eubacteria with active site on periplasmic side of cell membrane.
124255411322223232248Water nucleophile; water bound by two Asp; all membrane-bound endopeptidases known only from eubacteria with active site on cytoplasmic side of cell membrane.
19161562720271933141615151720172020221518391Cysteine nucleophile; catalytic residues in the order Cys, His, Asn (or Asp) in sequence
32246614104345547104635107Cysteine nucleophile; catalytic residues in the order His, Cys in sequence
251443213122233442250Cysteine nucleophile; catalytic residues in the order His, Glu (or Asp), Cys in sequence
111111111111113Cysteine nucleophile; catalytic residues in the order Glu, Cys, His in sequence
11Cysteine nucleophile; catalytic residues in the order His, Cys in sequence
1113Cysteine nucleophile; catalytic residues in the order His, Cys in sequence
11Water nucleophile; water bound by Gln and Glu; all endopeptidases
1111116Water nucleophile; water bound by Glu; all self-cleaving endopeptidases
52217666136545745841144115Families of peptidase inhibitors not assigned to clans
235
11
211116
112
11
112
11123311313111312231
122229
11114
11112112121211111122Families of metallopeptidases not assigned to clans
35151564546351438102022194925134619251115523Water nucleophile; water bound by single zinc ion ligated to two His (within the motif HEXXH) and Glu, His or Asp
122734413343315262359Water nucleophile; water bound by single zinc ion ligated to His, Glu (within the motif HXXE) and His
22212132211312111129Water nucleophile; water bound by single zinc ion ligated to two His (within the motif HXXEH) and Glu
2121524243343325354361Water nucleophile; water bound by two zinc ions ligated by Lys, Asp, Asp, Asp, Glu
7542117991578887878811910168Water nucleophile; water bound by two cobalt or manganese ions ligated by Asp, Asp, His, Glu, Glu
111194251325333079911181512271325129328Water nucleophile; water bound by two zinc ions ligated by His (or Asp), Asp, Glu, Asp (or Glu), His
4221118118112747542125955125Water nucleophile; water bound by two zinc ions ligated by His, His or Asp, Lys or Glu, His, His.
112121111111111118Water nucleophile; water bound by single zinc ion ligated to two His (within the motif HEXXH) and Asp; membrane proteins with intramembrane active site.
6343546844437676454699Water nucleophile; water bound by single zinc ion ligated to two His and Asp (within the motif HSHP(X)9D)
111212111112116Asparagine nucleophile; catalytic residues in the order Asp, Asn in sequence; all self-processing endopeptidases
912213105312851213178Serine or cysteine nucleophile; catalytic residues in the order His, Asp, Ser (or Cys) in sequence; all endopeptidases
15191893021272432171717211918162019191919416Threonine, serine or cysteine nucleophile at the N-terminus of mature enzyme
54335476645324636395497Serine or cysteine nucleophile; catalytic residues in the order Cys (or Ser), His, Glu in sequence.
111115Cysteine nucleophile at the N-terminus of mature enzyme; catalytic residues in the order Cys, Thr, His
113111111111421122Serine or threonine nucleophile; N-terminal nucleophile
21522102942127510895215681021202Serine nucleophile; catalytic residues in the order Asp, His, Ser in sequence in family S8, but family S53 differs
4471251283671001061426459416188734480499849351,391Serine nucleophile; catalytic residues in the order Ser, Asp, His in sequence
110765815163426211241312127Serine nucleophile; catalytic residues in the order Ser, Lys (within the motif SXXK) in sequence
554195767576458355577116Serine nucleophile; catalytic residues in the order Ser, Lys (or His) in sequence
111115Serine nucleophile; catalytic residues in the order Ser, Lys in sequence
12122231512123132222141Serine nucleophile; catalytic residues in the order Ser, His, Asp in sequence
11Serine nucleophile; catalytic residues in the order His, Ser within the motif HXS.
112Serine nucleophile; catalytic residues in the order Ser, Glu, His
332232311044775514454483Serine nucleophile; transmembrane protein with catalytic residues in the order Ser, His embedded in the membrane
11Families of peptidases of unknown catalytic mechanism not assigned to clans
112121211111111119
11
241622152629232832201521142426191516311518449
1262112
112