Due to a planned NERSC power outage, JGI portals will be unavailable 6:00am PDT July 10 - 11:59pm PDT July 14. System Status updates available here.
Peptidases • Pleosporales
Annotations/GenomesAalte1Aaoar1Alalt1Alalte1Albra1Altal1Altalt1Altar1Altbr1Altca1Altcar1Altci1Altcr1Altda1Altfr1Altga1Altli1Altlo1Altma1Altpo1Altro1Altso1Altta1Altte1Alttom1Amal3063Amal3064Amnli1Ampqui1Ascra1Bimnz1Boeex1Bysci1Clael1Cloaq1Cocca1CocheC4_1CocheC5_3Coclu2Cocmi1Cocsa1Cocvi1Corca1Cucbe1Currey1Decga1DelFL0756_1Delco1Denna1Didex1Didma1Dotsy1Epini1Fenfe1Herpot1_1Karrh1Lenfl1Lepmu1Linin1Lopma1Lopnu1Macan1Maseb1Masph1Melpu1Ophdi1Parch1Parchr1Parsp1Perma1PhaPMI808Phapo1Phomu1Photr1PlePMI138_1Plesi1Polfu1Pyrly1Pyrsp1Pyrtr1Pyrtt1Setho1Settu3Settur3Spofi1Stano2Stasp1Stely1Trepe1Veren1Wesor1TotalAnnotation Description
Merops
37640638837328138638139928234235838834836137942438738835534035736239438736239039837730431641440739332641533534637234132633034749032832128730327339333130530235733446742242826037643650334833935546639045844146052840840435734138035343643443129730541332432225034345425741635524833,570
151319141215151512131416141416171517131619141517131716242514151513191822222918212222171613171710182314101714161721102313321612312025252420172315181523122023201326221717161316112218141,587Water nucleophile; water bound by two Asp from monomer or dimer; all endopeptidases, from eukaryote organisms, viruses or virus-like organisms
1113Water nucleophile; water bound by two Asp; all membrane-bound endopeptidases known only from eubacteria with active site on periplasmic side of cell membrane.
121011127111213791113911121213129101010131312131274488777101012111010101287568776367686478946551010106118951257108108889947124773781Water nucleophile; water bound by two Asp; all membrane-bound endopeptidases known only from eubacteria with active site on cytoplasmic side of cell membrane.
112Water nucleophile; water bound by two Asp
282828261928273019283029272426263228293127242727312928292426292927262926282821242727292831262727322823272734343231222428293129263127343431333131282535322828282624342223212532192829262,526Cysteine nucleophile; catalytic residues in the order Cys, His, Asn (or Asp) in sequence
4444344634444344443444444445444554344444444423434433534465443444554444444544444444443344543361Cysteine nucleophile; catalytic residues in the order His, Cys in sequence
1111111111111111111111111111111211211111111111121111111211113111112111111111111111211111197Cysteine nucleophile; catalytic residues in the order His, Glu (or Asp), Cys in sequence
232212221222222212222222222221212121111111221122312132331313223222233221222222111112221211162Cysteine nucleophile; catalytic residues in the order Glu, Cys, His in sequence
11Cysteine nucleophile; catalytic residues in the order His, Cys in sequence
11211111111111111111111125Cysteine nucleophile; catalytic residues in the order Cys, His, His in sequence
111111111111111111111111111111111111111111111111111111111111111111111111111111111111111188Cysteine nucleophile; catalytic residues in the order His, Cys in sequence
112122222111131121112212212113122135513332221111321212213223143233211214122111331111111157Water nucleophile; water bound by Gln and Glu; all endopeptidases
5555455543353155553353554555555554455555555454565536455544455455554455544545544554554444554414Families of peptidase inhibitors not assigned to clans
1113
11111117
212212222222222222221222222111111211111111111211111221111211111111111111111111221111111111121
45445564556456544453464465464392375333232373353443144257655653544545811454634463357443563663409
26322433245243434342543442355410574656654666442454435535883354457883498657544375234553463554410Families of metallopeptidases not assigned to clans
1519161613171717131218161414182218151512131719151715201416131620221619121211191311132417111478171412171616261716111615201817142716211917212418151520202224201411201210101620101814101,467Water nucleophile; water bound by single zinc ion ligated to two His (within the motif HEXXH) and Glu, His or Asp
6666877587758766576576567656786855577777777724345755746566236845487758778764577768775776344548Water nucleophile; water bound by single zinc ion ligated to His, Glu (within the motif HXXE) and His
111111611211111117313213321212121111111111111111111211211111111121111111211211112111212129Water nucleophile; water bound by single zinc ion ligated to two His (within the motif HXXEH) and Glu
11Water nucleophile; water bound by two zinc ions ligated by Lys, Asp, Asp, Asp, Glu
66776561066767777667667777567577697765666668656769757656856579686796789767667775659676754687595Water nucleophile; water bound by two cobalt or manganese ions ligated by Asp, Asp, His, Glu, Glu
233226251624222216242323242623262522222521222423212323262525272927242423242623212119342421202022262519232525342926212727332826143326293028322628292523262633321920252224192229172518192,224Water nucleophile; water bound by two zinc ions ligated by His (or Asp), Asp, Glu, Asp (or Glu), His
11191111121210131210121011111211101111121511121111131310891317111014109998111123810111181310145149149131313171911141412811111216161013981215151112108131371113914971,055Water nucleophile; water bound by two zinc ions ligated by His, His or Asp, Lys or Glu, His, His.
11111117Water nucleophile; water bound by single zinc ion ligated to two His and Asp (within the motifs HXXXD and HXH)
3434344534344434544433444553333332333343334333333433333333333333344433333333343332323332333299Water nucleophile; water bound by single zinc ion ligated to two His and Asp (within the motif HSHP(X)9D)
11111117Water nucleophile; water bound by single zinc ion ligated to Asp, His and His.
112Asparagine nucleophile; catalytic residues in the order Asp, Asn in sequence; all self-processing endopeptidases
424444554334344545324344345342434222322222321212223132544322324332445523433214322233133322272Serine or cysteine nucleophile; catalytic residues in the order His, Asp, Ser (or Cys) in sequence; all endopeptidases
21202222212221232121202220212124212121192121222121222121201724212321212119202221202120232120192119201920212122232122232322212122222223222322242319202021232320192022222219212292021211,914Threonine, serine or cysteine nucleophile at the N-terminus of mature enzyme
91199109912109810989131097811891089116591189698899988108667510797967111058898967811810171012118851091089149868126877793Serine or cysteine nucleophile; catalytic residues in the order Cys (or Ser), His, Glu in sequence.
111111111211121111111211111111134Cysteine nucleophile at the N-terminus of mature enzyme; catalytic residues in the order Cys, Thr, His
111131113111111111111111111111111111111111111111111111111211111211111111111111221111193Serine or threonine nucleophile; N-terminal nucleophile
1112121291312139121212111012121314121312161411101311131211221616715161416131314161599128811910101211181913101315211311112291213221512111113111612111013141416158121313111281,154Serine nucleophile; catalytic residues in the order Asp, His, Ser in sequence in family S8, but family S53 differs
1521591501468715615514187124128156126144150171148159131117126134161155133151160140961181521631501171651141231321271181111252061171289711888160116119105132120195160172801392022121221151281771491951801842381471651261181441271831661879798161113110771331941051701377212,742Serine nucleophile; catalytic residues in the order Ser, Asp, His in sequence
14101313612121061213131212111211101111121212131313128556131441575564661867342887889151617213111994102512131415141212119107171417661023471351472905Serine nucleophile; catalytic residues in the order Ser, Lys (within the motif SXXK) in sequence
3333333333333332333143333335233333433333334243233233334333543333233344333333333223332332334274Serine nucleophile; catalytic residues in the order Ser, Lys (or His) in sequence
11Serine nucleophile; catalytic residues in the order Ser, Lys in sequence
22222122222222222222221222212112122132111122222221212111221211212211122212112222222222121151Serine nucleophile; catalytic residues in the order Ser, His, Asp in sequence
112Serine nucleophile; catalytic residues in the order His, Ser within the motif HXS.
11114Serine nucleophile; catalytic residues in the order Ser, Glu, His
3343233322242223333342242224433433433343435533255544444443442455454453444555533344434553543322Serine nucleophile; transmembrane protein with catalytic residues in the order Ser, His embedded in the membrane
111111112111114Families of peptidases of unknown catalytic mechanism not assigned to clans
11112111111111111211111111111111111111111111111111153
131213131513101615141413141113121412131710121113151412141011171016131712131510111214111011101314121110111114111415816121513111520131212141416111111169121412111015101211101271617121,157
11
1111112111111111111121
11
11114
42131112112111122132413221223123231221521371513342221333422143332222216721170