Peptidases • Flagelloscypha sp. PMI_526 v1.0
Annotations/GenomesAuramp1Denbi1Fishe1FlaPMI526_1Niavib1Schco3TotalAnnotation Description
Merops
3516992745202873452,476
226130361529193Water nucleophile; water bound by two Asp from monomer or dimer; all endopeptidases, from eukaryote organisms, viruses or virus-like organisms
33241215Water nucleophile; water bound by two Asp; all membrane-bound endopeptidases known only from eubacteria with active site on cytoplasmic side of cell membrane.
233717231620136Cysteine nucleophile; catalytic residues in the order Cys, His, Asn (or Asp) in sequence
5136116546Cysteine nucleophile; catalytic residues in the order His, Cys in sequence
2731215Cysteine nucleophile; catalytic residues in the order His, Glu (or Asp), Cys in sequence
11Cysteine nucleophile: catalytic residues in the order Cys, His in sequence
14117Water nucleophile; water bound by Gln and Glu; all endopeptidases
210232221Families of peptidase inhibitors not assigned to clans
11
11
112
2111128
716282742
33284323Families of metallopeptidases not assigned to clans
342012301922137Water nucleophile; water bound by single zinc ion ligated to two His (within the motif HEXXH) and Glu, His or Asp
21267220Water nucleophile; water bound by single zinc ion ligated to His, Glu (within the motif HXXE) and His
321118Water nucleophile; water bound by single zinc ion ligated to two His (within the motif HXXEH) and Glu
1311129Water nucleophile; water bound by two zinc ions ligated by Lys, Asp, Asp, Asp, Glu
812101091059Water nucleophile; water bound by two cobalt or manganese ions ligated by Asp, Asp, His, Glu, Glu
264318331823161Water nucleophile; water bound by two zinc ions ligated by His (or Asp), Asp, Glu, Asp (or Glu), His
12321215121295Water nucleophile; water bound by two zinc ions ligated by His, His or Asp, Lys or Glu, His, His.
1112117Water nucleophile; water bound by single zinc ion ligated to two His (within the motif HEXXH) and Asp; membrane proteins with intramembrane active site.
67666536Water nucleophile; water bound by single zinc ion ligated to two His and Asp (within the motif HSHP(X)9D)
213Asparagine nucleophile; catalytic residues in the order Asp, Asn in sequence; all self-processing endopeptidases
11Asparagine nucleophile; all self-processing endopeptidases
11Serine or cysteine nucleophile; catalytic residues in the order His, Asp, Ser (or Cys) in sequence; all endopeptidases
243324232322149Threonine, serine or cysteine nucleophile at the N-terminus of mature enzyme
11225135763Serine or cysteine nucleophile; catalytic residues in the order Cys (or Ser), His, Glu in sequence.
415Serine or threonine nucleophile; N-terminal nucleophile
713655366123Serine nucleophile; catalytic residues in the order Asp, His, Ser in sequence in family S8, but family S53 differs
1202618218279132856Serine nucleophile; catalytic residues in the order Ser, Asp, His in sequence
5191163347Serine nucleophile; catalytic residues in the order Ser, Lys (within the motif SXXK) in sequence
36374326Serine nucleophile; catalytic residues in the order Ser, Lys (or His) in sequence
1121117Serine nucleophile; catalytic residues in the order Ser, His, Asp in sequence
44441421Serine nucleophile; transmembrane protein with catalytic residues in the order Ser, His embedded in the membrane
1111116
13641313912124
11