Peptidases • Trematosphaeria pertusa CBS 122368 v1.0
Annotations/GenomesAltbr1Amnli1Cocca1CocheC4_1CocheC5_3Coclu1Coclu2Cocmi1Cocsa1Cocvi1Cucbe1Didex1Dotsy1Karrh1Lenfl1Lepmu1Lopma1Melpu1Plesi1Pyrtr1Pyrtt1Settu1Spofi1Stano1Stano2Trepe1TotalAnnotation Description
Merops
2823773353463723413263303473283313024224282604364663532973053242503434168,317
122422222918212222162310172110132012132616161322440Water nucleophile; water bound by two Asp from monomer or dimer; all endopeptidases, from eukaryote organisms, viruses or virus-like organisms
7710101211101010873864857889477186Water nucleophile; water bound by two Asp; all membrane-bound endopeptidases known only from eubacteria with active site on cytoplasmic side of cell membrane.
11Water nucleophile; water bound by two Asp
192926282821242727282827323122283132262422212528634Cysteine nucleophile; catalytic residues in the order Cys, His, Asn (or Asp) in sequence
35444444444346545444433598Cysteine nucleophile; catalytic residues in the order His, Cys in sequence
1111111111111211111121125Cysteine nucleophile; catalytic residues in the order His, Glu (or Asp), Cys in sequence
12111111121133112211122235Cysteine nucleophile; catalytic residues in the order Glu, Cys, His in sequence
11111117Cysteine nucleophile; catalytic residues in the order Cys, His, His in sequence
1111111111111111111111123Cysteine nucleophile; catalytic residues in the order His, Cys in sequence
21355133321312234411311156Water nucleophile; water bound by Gln and Glu; all endopeptidases
455555555456544555555445115Families of peptidase inhibitors not assigned to clans
112
21111111111211211122111129
56333232333476564435435698
255665466445883584235345116Families of metallopeptidases not assigned to clans
131412121119131113171417171611152720141112101618353Water nucleophile; water bound by single zinc ion ligated to two His (within the motif HEXXH) and Glu, His or Asp
867777777775566344767573145Water nucleophile; water bound by single zinc ion ligated to His, Glu (within the motif HXXE) and His
12111111111121111121121229Water nucleophile; water bound by single zinc ion ligated to two His (within the motif HXXEH) and Glu
676566666677856777656676150Water nucleophile; water bound by two cobalt or manganese ions ligated by Asp, Asp, His, Glu, Glu
162623242623212119242523292621273326192022192225560Water nucleophile; water bound by two zinc ions ligated by His (or Asp), Asp, Glu, Asp (or Glu), His
1210109998111181059131317121212101371114255Water nucleophile; water bound by two zinc ions ligated by His, His or Asp, Lys or Glu, His, His.
111115Water nucleophile; water bound by single zinc ion ligated to two His and Asp (within the motifs HXXXD and HXH)
33333433334333333333333374Water nucleophile; water bound by single zinc ion ligated to two His and Asp (within the motif HSHP(X)9D)
1113Water nucleophile; water bound by single zinc ion ligated to Asp, His and His.
43232222222144323222313258Serine or cysteine nucleophile; catalytic residues in the order His, Asp, Ser (or Cys) in sequence; all endopeptidases
212121192022212021232020232122232221192021192120501Threonine, serine or cysteine nucleophile at the N-terminus of mature enzyme
106889998887711105875899688191Serine or cysteine nucleophile; catalytic residues in the order Cys (or Ser), His, Glu in sequence.
1122118Cysteine nucleophile at the N-terminus of mature enzyme; catalytic residues in the order Cys, Thr, His
31111111111111111112124Serine or threonine nucleophile; N-terminal nucleophile
91316141613131416991019131015221613141581211320Serine nucleophile; catalytic residues in the order Asp, His, Ser in sequence in family S8, but family S53 differs
87140114123132127118111125117116105160172802021771279798114771331703,022Serine nucleophile; catalytic residues in the order Ser, Asp, His in sequence
68755646668816172112576624714192Serine nucleophile; catalytic residues in the order Ser, Lys (within the motif SXXK) in sequence
35333333322333342322323369Serine nucleophile; catalytic residues in the order Ser, Lys (or His) in sequence
21132111121211211122222136Serine nucleophile; catalytic residues in the order Ser, His, Asp in sequence
112Serine nucleophile; catalytic residues in the order Ser, Glu, His
24333434355444344534445592Serine nucleophile; transmembrane protein with catalytic residues in the order Ser, His embedded in the membrane
11114Families of peptidases of unknown catalytic mechanism not assigned to clans
111111111110
1514121315101112141011111415812209111012111016296
112116
422312321151323221747