Peptidases • Phialocephala scopiformis 5WS22E1 v1.0
Annotations/GenomesAscsa1Botci1Cadsp1Chalo1Glalo1Marbr1Melbi2Perma1Phisc1Rhier1Sclsc1TotalAnnotation Description
Merops
2943247256723692464955286484192774,997
1518315020102717413212273Water nucleophile; water bound by two Asp from monomer or dimer; all endopeptidases, from eukaryote organisms, viruses or virus-like organisms
11Water nucleophile; water bound by two Asp; all membrane-bound endopeptidases known only from eubacteria with active site on periplasmic side of cell membrane.
5417165813111776109Water nucleophile; water bound by two Asp; all membrane-bound endopeptidases known only from eubacteria with active site on cytoplasmic side of cell membrane.
1921372925233533263018296Cysteine nucleophile; catalytic residues in the order Cys, His, Asn (or Asp) in sequence
3235235445238Cysteine nucleophile; catalytic residues in the order His, Cys in sequence
111312123116Cysteine nucleophile; catalytic residues in the order His, Glu (or Asp), Cys in sequence
53211331120Cysteine nucleophile; catalytic residues in the order Glu, Cys, His in sequence
1124Cysteine nucleophile; catalytic residues in the order Cys, His, His in sequence
111111118Cysteine nucleophile; catalytic residues in the order His, Cys in sequence
43418426387261Water nucleophile; water bound by Gln and Glu; all endopeptidases
11Water nucleophile; water bound by Glu; all self-cleaving endopeptidases
4554445554550Families of peptidase inhibitors not assigned to clans
11114
1113
213
221121122115
34773331152351
11
54108327873360Families of metallopeptidases not assigned to clans
9933232116172121128190Water nucleophile; water bound by single zinc ion ligated to two His (within the motif HEXXH) and Glu, His or Asp
1321221811325Water nucleophile; water bound by single zinc ion ligated to His, Glu (within the motif HXXE) and His
2412122112220Water nucleophile; water bound by single zinc ion ligated to two His (within the motif HXXEH) and Glu
88111094109129898Water nucleophile; water bound by two cobalt or manganese ions ligated by Asp, Asp, His, Glu, Glu
1620413826182732412017296Water nucleophile; water bound by two zinc ions ligated by His (or Asp), Asp, Glu, Asp (or Glu), His
1282523149181626118170Water nucleophile; water bound by two zinc ions ligated by His, His or Asp, Lys or Glu, His, His.
112Water nucleophile; water bound by single zinc ion ligated to two His and Asp (within the motifs HXXXD and HXH)
4444434344442Water nucleophile; water bound by single zinc ion ligated to two His and Asp (within the motif HSHP(X)9D)
1111116Water nucleophile; water bound by single zinc ion ligated to Asp, His and His.
1374234532236Serine or cysteine nucleophile; catalytic residues in the order His, Asp, Ser (or Cys) in sequence; all endopeptidases
2122272724212422262525264Threonine, serine or cysteine nucleophile at the N-terminus of mature enzyme
3613116351764478Serine or cysteine nucleophile; catalytic residues in the order Cys (or Ser), His, Glu in sequence.
22112111112Serine or threonine nucleophile; N-terminal nucleophile
112Families of serine peptidases not assigned to clans
1712403515122515342512242Serine nucleophile; catalytic residues in the order Asp, His, Ser in sequence in family S8, but family S53 differs
110131315290144691842382951601002,036Serine nucleophile; catalytic residues in the order Ser, Asp, His in sequence
56302172221423134147Serine nucleophile; catalytic residues in the order Ser, Lys (within the motif SXXK) in sequence
3333323433232Serine nucleophile; catalytic residues in the order Ser, Lys (or His) in sequence
11Serine nucleophile; catalytic residues in the order Ser, Lys in sequence
1112112112114Serine nucleophile; catalytic residues in the order Ser, His, Asp in sequence
1113Serine nucleophile; catalytic residues in the order Ser, Glu, His
2135346323335Serine nucleophile; transmembrane protein with catalytic residues in the order Ser, His embedded in the membrane
111126Families of peptidases of unknown catalytic mechanism not assigned to clans
111111111110
1512301413112314151717181
211217
1146446228