Peptidases • Monascus purpureus v1.0
Annotations/GenomesAspnid1Eurhe1Gymau1Monpu1Monru1Mycgr3Penex1Theau1TotalAnnotation Description
Merops
2912442242432623423702142,190
48108922111082Water nucleophile; water bound by two Asp from monomer or dimer; all endopeptidases, from eukaryote organisms, viruses or virus-like organisms
415Water nucleophile; water bound by two Asp; all membrane-bound endopeptidases known only from eubacteria with active site on periplasmic side of cell membrane.
33724349769Water nucleophile; water bound by two Asp; all membrane-bound endopeptidases known only from eubacteria with active site on cytoplasmic side of cell membrane.
1031253334273427221Cysteine nucleophile; catalytic residues in the order Cys, His, Asn (or Asp) in sequence
3323323322Cysteine nucleophile; catalytic residues in the order His, Cys in sequence
122221111Cysteine nucleophile; catalytic residues in the order His, Glu (or Asp), Cys in sequence
1111217Cysteine nucleophile; catalytic residues in the order Glu, Cys, His in sequence
11Cysteine nucleophile; active peptidase is a homodimer with active site His and Glu from one monomer and Cys from the other. Catalytic residues in the order His, Glu, Cys in each monomer.
112Cysteine nucleophile; catalytic residues in the order Cys, His, His in sequence
11Cysteine nucleophile; catalytic residues in the order His, Cys in sequence
432253221Water nucleophile; water bound by Gln and Glu; all endopeptidases
5665554541Families of peptidase inhibitors not assigned to clans
11
11
11
11
3112213114
112331213
7722327333Families of metallopeptidases not assigned to clans
161213107281311110Water nucleophile; water bound by single zinc ion ligated to two His (within the motif HEXXH) and Glu, His or Asp
121141111Water nucleophile; water bound by single zinc ion ligated to His, Glu (within the motif HXXE) and His
1113Water nucleophile; water bound by single zinc ion ligated to two His (within the motif HXXEH) and Glu
11Water nucleophile; water bound by two zinc ions ligated by Lys, Asp, Asp, Asp, Glu
54677108653Water nucleophile; water bound by two cobalt or manganese ions ligated by Asp, Asp, His, Glu, Glu
4016151921173312173Water nucleophile; water bound by two zinc ions ligated by His (or Asp), Asp, Glu, Asp (or Glu), His
8891013615877Water nucleophile; water bound by two zinc ions ligated by His, His or Asp, Lys or Glu, His, His.
1333344223Water nucleophile; water bound by single zinc ion ligated to two His and Asp (within the motif HSHP(X)9D)
112Water nucleophile; water bound by single zinc ion ligated to Asp, His and His.
2226Serine or cysteine nucleophile; catalytic residues in the order His, Asp, Ser (or Cys) in sequence; all endopeptidases
1720192020211822157Threonine, serine or cysteine nucleophile at the N-terminus of mature enzyme
47357613348Serine or cysteine nucleophile; catalytic residues in the order Cys (or Ser), His, Glu in sequence.
1111116Serine or threonine nucleophile; N-terminal nucleophile
46699167562Serine nucleophile; catalytic residues in the order Asp, His, Ser in sequence in family S8, but family S53 differs
617065657411913258644Serine nucleophile; catalytic residues in the order Ser, Asp, His in sequence
11689811347Serine nucleophile; catalytic residues in the order Ser, Lys (within the motif SXXK) in sequence
1423235222Serine nucleophile; catalytic residues in the order Ser, Lys (or His) in sequence
2122232115Serine nucleophile; catalytic residues in the order Ser, His, Asp in sequence
11Serine nucleophile; catalytic residues in the order Ser, Glu, His
2221232216Serine nucleophile; transmembrane protein with catalytic residues in the order Ser, His embedded in the membrane
31228Families of peptidases of unknown catalytic mechanism not assigned to clans
111111118
8128912914981
11
11
1113
38733323564