Peptidases • Chaetosphaeriales
Annotations/GenomesChain1CodFL1790_1ThoPMI491_1TotalAnnotation Description
Merops
4276829882,097
285467149Water nucleophile; water bound by two Asp from monomer or dimer; all endopeptidases, from eukaryote organisms, viruses or virus-like organisms
11Water nucleophile; water bound by two Asp; all membrane-bound endopeptidases known only from eubacteria with active site on periplasmic side of cell membrane.
47819Water nucleophile; water bound by two Asp; all membrane-bound endopeptidases known only from eubacteria with active site on cytoplasmic side of cell membrane.
25214187Cysteine nucleophile; catalytic residues in the order Cys, His, Asn (or Asp) in sequence
33612Cysteine nucleophile; catalytic residues in the order His, Cys in sequence
112Cysteine nucleophile; catalytic residues in the order His, Glu (or Asp), Cys in sequence
1225Cysteine nucleophile; catalytic residues in the order Glu, Cys, His in sequence
11Cysteine nucleophile; catalytic residues in the order Cys, His, His in sequence
1113Cysteine nucleophile; catalytic residues in the order His, Cys in sequence
10211849Water nucleophile; water bound by Gln and Glu; all endopeptidases
2349Water nucleophile; water bound by Glu; all self-cleaving endopeptidases
35513Families of peptidase inhibitors not assigned to clans
1113
1124
27918
11
271120Families of metallopeptidases not assigned to clans
21243984Water nucleophile; water bound by single zinc ion ligated to two His (within the motif HEXXH) and Glu, His or Asp
1236Water nucleophile; water bound by single zinc ion ligated to His, Glu (within the motif HXXE) and His
2327Water nucleophile; water bound by single zinc ion ligated to two His (within the motif HXXEH) and Glu
10111334Water nucleophile; water bound by two cobalt or manganese ions ligated by Asp, Asp, His, Glu, Glu
203550105Water nucleophile; water bound by two zinc ions ligated by His (or Asp), Asp, Glu, Asp (or Glu), His
20295099Water nucleophile; water bound by two zinc ions ligated by His, His or Asp, Lys or Glu, His, His.
11Water nucleophile; water bound by single zinc ion ligated to two His (within the motif HEXXH) and Asp; membrane proteins with intramembrane active site.
11Water nucleophile; water bound by single zinc ion ligated to two His and Asp (within the motifs HXXXD and HXH)
3227Water nucleophile; water bound by single zinc ion ligated to two His and Asp (within the motif HSHP(X)9D)
1124Water nucleophile; water bound by single zinc ion ligated to Asp, His and His.
51116Serine or cysteine nucleophile; catalytic residues in the order His, Asp, Ser (or Cys) in sequence; all endopeptidases
24283385Threonine, serine or cysteine nucleophile at the N-terminus of mature enzyme
4101428Serine or cysteine nucleophile; catalytic residues in the order Cys (or Ser), His, Glu in sequence.
112Cysteine nucleophile at the N-terminus of mature enzyme; catalytic residues in the order Cys, Thr, His
2439Serine or threonine nucleophile; N-terminal nucleophile
323867137Serine nucleophile; catalytic residues in the order Asp, His, Ser in sequence in family S8, but family S53 differs
176290443909Serine nucleophile; catalytic residues in the order Ser, Asp, His in sequence
9263469Serine nucleophile; catalytic residues in the order Ser, Lys (within the motif SXXK) in sequence
1337Serine nucleophile; catalytic residues in the order Ser, Lys (or His) in sequence
1214Serine nucleophile; catalytic residues in the order Ser, His, Asp in sequence
1236Serine nucleophile; catalytic residues in the order Ser, Glu, His
25411Serine nucleophile; transmembrane protein with catalytic residues in the order Ser, His embedded in the membrane
3115Families of peptidases of unknown catalytic mechanism not assigned to clans
1113
6161537
112
11
361322