Peptidases • Cryptophyceae sp. CCMP2293 v1.0
Annotations/GenomesCrypto2293_1Emihu1Guith1Pavlov2436_1TotalAnnotation Description
Merops
6116224893162,038
886325Water nucleophile; water bound by two Asp from monomer or dimer; all endopeptidases, from eukaryote organisms, viruses or virus-like organisms
124411Water nucleophile; water bound by two Asp; all membrane-bound endopeptidases known only from eubacteria with active site on cytoplasmic side of cell membrane.
45564535181Cysteine nucleophile; catalytic residues in the order Cys, His, Asn (or Asp) in sequence
855321Cysteine nucleophile; catalytic residues in the order His, Cys in sequence
234312Cysteine nucleophile; catalytic residues in the order His, Glu (or Asp), Cys in sequence
213Cysteine nucleophile; catalytic residues in the order Glu, Cys, His in sequence
315110Cysteine nucleophile; catalytic residues in the order His, Cys in sequence
269421Families of peptidase inhibitors not assigned to clans
4116
123
11
11
123
11
15113231
224
11
123
213
112Families of metallopeptidases not assigned to clans
113294017199Water nucleophile; water bound by single zinc ion ligated to two His (within the motif HEXXH) and Glu, His or Asp
7811329Water nucleophile; water bound by single zinc ion ligated to His, Glu (within the motif HXXE) and His
1178834Water nucleophile; water bound by single zinc ion ligated to two His (within the motif HXXEH) and Glu
644216Water nucleophile; water bound by two zinc ions ligated by Lys, Asp, Asp, Asp, Glu
811101039Water nucleophile; water bound by two cobalt or manganese ions ligated by Asp, Asp, His, Glu, Glu
12910637Water nucleophile; water bound by two zinc ions ligated by His (or Asp), Asp, Glu, Asp (or Glu), His
5159635Water nucleophile; water bound by two zinc ions ligated by His, His or Asp, Lys or Glu, His, His.
2226Water nucleophile; water bound by single zinc ion ligated to two His (within the motif HEXXH) and Asp; membrane proteins with intramembrane active site.
22Water nucleophile; water bound by single zinc ion ligated to two His and Asp (within the motifs HXXXD and HXH)
546520Water nucleophile; water bound by single zinc ion ligated to two His and Asp (within the motif HSHP(X)9D)
11Water nucleophile; water bound by single zinc ion ligated to Asp, His and His.
12238Asparagine nucleophile; catalytic residues in the order Asp, Asn in sequence; all self-processing endopeptidases
11308655Serine or cysteine nucleophile; catalytic residues in the order His, Asp, Ser (or Cys) in sequence; all endopeptidases
30502624130Threonine, serine or cysteine nucleophile at the N-terminus of mature enzyme
71581040Serine or cysteine nucleophile; catalytic residues in the order Cys (or Ser), His, Glu in sequence.
66Cysteine nucleophile at the N-terminus of mature enzyme; catalytic residues in the order Cys, Thr, His
213Serine or threonine nucleophile; N-terminal nucleophile
52171144Serine nucleophile; catalytic residues in the order Asp, His, Ser in sequence in family S8, but family S53 differs
115213111102541Serine nucleophile; catalytic residues in the order Ser, Asp, His in sequence
4143223Serine nucleophile; catalytic residues in the order Ser, Lys (within the motif SXXK) in sequence
3105422Serine nucleophile; catalytic residues in the order Ser, Lys (or His) in sequence
11Serine nucleophile; catalytic residues in the order Ser, Lys in sequence
31214111104Serine nucleophile; catalytic residues in the order Ser, His, Asp in sequence
11Serine nucleophile; catalytic residues in the order His, Ser within the motif HXS.
5910327Serine nucleophile; transmembrane protein with catalytic residues in the order Ser, His embedded in the membrane
1113Families of peptidases of unknown catalytic mechanism not assigned to clans
22
134446820266
11