Peptidases • Multifurca ochricompacta BPL690 v1.0
Annotations/GenomesGlocon1Lacqui1Lacsub1Lacvol1Muloch1Rusbre1Ruscom1Rusdis1Rusrug1TotalAnnotation Description
Merops
3337032513042952532132273172,896
205123343220182337258Water nucleophile; water bound by two Asp from monomer or dimer; all endopeptidases, from eukaryote organisms, viruses or virus-like organisms
12121111111Water nucleophile; water bound by two Asp; all membrane-bound endopeptidases known only from eubacteria with active site on cytoplasmic side of cell membrane.
152612131311111370184Cysteine nucleophile; catalytic residues in the order Cys, His, Asn (or Asp) in sequence
311636171291279Cysteine nucleophile; catalytic residues in the order His, Cys in sequence
1111116Cysteine nucleophile; catalytic residues in the order His, Glu (or Asp), Cys in sequence
11Cysteine nucleophile; catalytic residues in the order Cys, His, His in sequence
21222222217Families of peptidase inhibitors not assigned to clans
11
111115
112116
62222611426
33224222222Families of metallopeptidases not assigned to clans
181420212212191816160Water nucleophile; water bound by single zinc ion ligated to two His (within the motif HEXXH) and Glu, His or Asp
11Water nucleophile; water bound by single zinc ion ligated to His, Glu (within the motif HXXE) and His
1211122212Water nucleophile; water bound by single zinc ion ligated to two His (within the motif HXXEH) and Glu
11114Water nucleophile; water bound by two zinc ions ligated by Lys, Asp, Asp, Asp, Glu
81281110877778Water nucleophile; water bound by two cobalt or manganese ions ligated by Asp, Asp, His, Glu, Glu
15121312128107998Water nucleophile; water bound by two zinc ions ligated by His (or Asp), Asp, Glu, Asp (or Glu), His
911910128810986Water nucleophile; water bound by two zinc ions ligated by His, His or Asp, Lys or Glu, His, His.
11111117Water nucleophile; water bound by single zinc ion ligated to two His (within the motif HEXXH) and Asp; membrane proteins with intramembrane active site.
1236Water nucleophile; water bound by single zinc ion ligated to two His and Asp (within the motifs HXXXD and HXH)
76657666655Water nucleophile; water bound by single zinc ion ligated to two His and Asp (within the motif HSHP(X)9D)
1113Asparagine nucleophile; catalytic residues in the order Asp, Asn in sequence; all self-processing endopeptidases
11Serine or cysteine nucleophile; catalytic residues in the order His, Asp, Ser (or Cys) in sequence; all endopeptidases
202021372019182018193Threonine, serine or cysteine nucleophile at the N-terminus of mature enzyme
64555433338Serine or cysteine nucleophile; catalytic residues in the order Cys (or Ser), His, Glu in sequence.
112Serine or threonine nucleophile; N-terminal nucleophile
2636781430106910480Serine nucleophile; catalytic residues in the order Asp, His, Ser in sequence in family S8, but family S53 differs
13313283989084646776827Serine nucleophile; catalytic residues in the order Ser, Asp, His in sequence
51421612325Serine nucleophile; catalytic residues in the order Ser, Lys (within the motif SXXK) in sequence
83442245436Serine nucleophile; catalytic residues in the order Ser, Lys (or His) in sequence
2911Serine nucleophile; catalytic residues in the order Ser, Lys in sequence
1111111119Serine nucleophile; catalytic residues in the order Ser, His, Asp in sequence
34345344232Serine nucleophile; transmembrane protein with catalytic residues in the order Ser, His embedded in the membrane
21111111110
17121014111291010105
11