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Peptidases • Harpellales
Annotations/GenomesSmicuMNP_2SmiculW2_1Smimuc2Zancul2TotalAnnotation Description
Merops
3282812202471,076
572519Water nucleophile; water bound by two Asp from monomer or dimer; all endopeptidases, from eukaryote organisms, viruses or virus-like organisms
11Water nucleophile; water bound by two Asp; all membrane-bound endopeptidases known only from eubacteria with active site on periplasmic side of cell membrane.
22116Water nucleophile; water bound by two Asp; all membrane-bound endopeptidases known only from eubacteria with active site on cytoplasmic side of cell membrane.
2418131570Cysteine nucleophile; catalytic residues in the order Cys, His, Asn (or Asp) in sequence
544821Cysteine nucleophile; catalytic residues in the order His, Cys in sequence
112Cysteine nucleophile; catalytic residues in the order His, Glu (or Asp), Cys in sequence
11Cysteine nucleophile; catalytic residues in the order Glu, Cys, His in sequence
22Cysteine nucleophile; catalytic residues in the order His, Cys in sequence
474419Families of peptidase inhibitors not assigned to clans
11
33
235212
22Families of metallopeptidases not assigned to clans
121161140Water nucleophile; water bound by single zinc ion ligated to two His (within the motif HEXXH) and Glu, His or Asp
532717Water nucleophile; water bound by single zinc ion ligated to two His (within the motif HXXEH) and Glu
973524Water nucleophile; water bound by two zinc ions ligated by Lys, Asp, Asp, Asp, Glu
1197835Water nucleophile; water bound by two cobalt or manganese ions ligated by Asp, Asp, His, Glu, Glu
2426221789Water nucleophile; water bound by two zinc ions ligated by His (or Asp), Asp, Glu, Asp (or Glu), His
43310Water nucleophile; water bound by two zinc ions ligated by His, His or Asp, Lys or Glu, His, His.
3238Water nucleophile; water bound by single zinc ion ligated to two His and Asp (within the motif HSHP(X)9D)
38383661173Serine or cysteine nucleophile; catalytic residues in the order His, Asp, Ser (or Cys) in sequence; all endopeptidases
42282119110Threonine, serine or cysteine nucleophile at the N-terminus of mature enzyme
1113Serine or cysteine nucleophile; catalytic residues in the order Cys (or Ser), His, Glu in sequence.
2114Serine or threonine nucleophile; N-terminal nucleophile
1818151768Serine nucleophile; catalytic residues in the order Asp, His, Ser in sequence in family S8, but family S53 differs
71564742216Serine nucleophile; catalytic residues in the order Ser, Asp, His in sequence
9105428Serine nucleophile; catalytic residues in the order Ser, Lys (or His) in sequence
213Serine nucleophile; catalytic residues in the order Ser, Lys in sequence
1113Serine nucleophile; catalytic residues in the order Ser, His, Asp in sequence
2226Serine nucleophile; transmembrane protein with catalytic residues in the order Ser, His embedded in the membrane
4116Families of peptidases of unknown catalytic mechanism not assigned to clans
21216
2421101267
11