Peptidases • Neocallimastix californiae G1 v1.0
Annotations/GenomesAnasp1Batde5Ganpr1Neosp1PirE2_1Pirfi3TotalAnnotation Description
Merops
3313143414433952282,052
11036271120Water nucleophile; water bound by two Asp from monomer or dimer; all endopeptidases, from eukaryote organisms, viruses or virus-like organisms
22Water nucleophile; water bound by two Asp; all membrane-bound endopeptidases known only from eubacteria with active site on periplasmic side of cell membrane.
2242212Water nucleophile; water bound by two Asp; all membrane-bound endopeptidases known only from eubacteria with active site on cytoplasmic side of cell membrane.
181921301620124Cysteine nucleophile; catalytic residues in the order Cys, His, Asn (or Asp) in sequence
113721131469Cysteine nucleophile; catalytic residues in the order His, Cys in sequence
22318Cysteine nucleophile; catalytic residues in the order His, Glu (or Asp), Cys in sequence
111115Cysteine nucleophile; catalytic residues in the order Glu, Cys, His in sequence
213Cysteine nucleophile; catalytic residues in the order His, Cys in sequence
11Cysteine nucleophile; catalytic residues in the order Cys, His, His in sequence
11Cysteine nucleophile; catalytic residues in the order His, Cys in sequence
11Water nucleophile; water bound by Glu; all self-cleaving endopeptidases
1255246557Families of peptidase inhibitors not assigned to clans
132131341
1113
11215
112
11
111488436Families of metallopeptidases not assigned to clans
483518456630242Water nucleophile; water bound by single zinc ion ligated to two His (within the motif HEXXH) and Glu, His or Asp
1612212Water nucleophile; water bound by single zinc ion ligated to His, Glu (within the motif HXXE) and His
11Water nucleophile; water bound by single zinc ion ligated to His, Asp and His
2211219Water nucleophile; water bound by single zinc ion ligated to two His (within the motif HXXEH) and Glu
32454321Water nucleophile; water bound by two zinc ions ligated by Lys, Asp, Asp, Asp, Glu
577106540Water nucleophile; water bound by two cobalt or manganese ions ligated by Asp, Asp, His, Glu, Glu
81116156561Water nucleophile; water bound by two zinc ions ligated by His (or Asp), Asp, Glu, Asp (or Glu), His
141311121Water nucleophile; water bound by two zinc ions ligated by His, His or Asp, Lys or Glu, His, His.
11114Water nucleophile; water bound by single zinc ion ligated to two His (within the motif HEXXH) and Asp; membrane proteins with intramembrane active site.
11Water nucleophile; water bound by two zinc ions ligated by Asp, Glu, His, His, Glu
56375531Water nucleophile; water bound by single zinc ion ligated to two His and Asp (within the motif HSHP(X)9D)
112Asparagine nucleophile; catalytic residues in the order Asp, Asn in sequence; all self-processing endopeptidases
9138131Serine or cysteine nucleophile; catalytic residues in the order His, Asp, Ser (or Cys) in sequence; all endopeptidases
151521311517114Threonine, serine or cysteine nucleophile at the N-terminus of mature enzyme
15531318Serine or cysteine nucleophile; catalytic residues in the order Cys (or Ser), His, Glu in sequence.
41218Serine or threonine nucleophile; N-terminal nucleophile
4324163817120Serine nucleophile; catalytic residues in the order Asp, His, Ser in sequence in family S8, but family S53 differs
914411912512758564Serine nucleophile; catalytic residues in the order Ser, Asp, His in sequence
11617Serine nucleophile; catalytic residues in the order Ser, Lys (within the motif SXXK) in sequence
65582329Serine nucleophile; catalytic residues in the order Ser, Lys (or His) in sequence
1132119Serine nucleophile; catalytic residues in the order Ser, His, Asp in sequence
22Serine nucleophile; catalytic residues in the order His, Ser within the motif HXS.
1036154543Serine nucleophile; transmembrane protein with catalytic residues in the order Ser, His embedded in the membrane
22Families of peptidases of unknown catalytic mechanism not assigned to clans
2142211
152417333415138
2226
224