Peptidases • Sistotremastrum suecicum v1.0
Annotations/GenomesAgabi_varbisH97_2Amamu1Aurde1Botbo1Cryne_JEC21_1Dacsp1Lacbi2PosplRSB12_1Schco2SerlaS7_9_2Sissu1Trave1Treme1Walse1TotalAnnotation Description
Merops
2873463741552993383343463274331491523,540
243748630324761286253383Water nucleophile; water bound by two Asp from monomer or dimer; all endopeptidases, from eukaryote organisms, viruses or virus-like organisms
112Water nucleophile; water bound by two Asp; all membrane-bound endopeptidases known only from eubacteria with active site on periplasmic side of cell membrane.
21413221111120Water nucleophile; water bound by two Asp; all membrane-bound endopeptidases known only from eubacteria with active site on cytoplasmic side of cell membrane.
18919111929132217151416202Cysteine nucleophile; catalytic residues in the order Cys, His, Asn (or Asp) in sequence
3411339641244366Cysteine nucleophile; catalytic residues in the order His, Cys in sequence
234212221120Cysteine nucleophile; catalytic residues in the order His, Glu (or Asp), Cys in sequence
11Cysteine nucleophile; catalytic residues in the order Glu, Cys, His in sequence
11Cysteine nucleophile; catalytic residues in the order Cys, His, His in sequence
11Cysteine nucleophile; catalytic residues in the order His, Cys in sequence
1321117Water nucleophile; water bound by Gln and Glu; all endopeptidases
466231122222345Families of peptidase inhibitors not assigned to clans
91827
11
11114
1212118
41521211621228
2722352222130Families of metallopeptidases not assigned to clans
19132110517141192296156Water nucleophile; water bound by single zinc ion ligated to two His (within the motif HEXXH) and Glu, His or Asp
11111117Water nucleophile; water bound by single zinc ion ligated to His, Glu (within the motif HXXE) and His
12124111114Water nucleophile; water bound by single zinc ion ligated to two His (within the motif HXXEH) and Glu
2112413216Water nucleophile; water bound by two zinc ions ligated by Lys, Asp, Asp, Asp, Glu
997810121086986102Water nucleophile; water bound by two cobalt or manganese ions ligated by Asp, Asp, His, Glu, Glu
1812201018161315191599174Water nucleophile; water bound by two zinc ions ligated by His (or Asp), Asp, Glu, Asp (or Glu), His
101211111291115912107129Water nucleophile; water bound by two zinc ions ligated by His, His or Asp, Lys or Glu, His, His.
1111111111111Water nucleophile; water bound by single zinc ion ligated to two His (within the motif HEXXH) and Asp; membrane proteins with intramembrane active site.
11Water nucleophile; water bound by single zinc ion ligated to two His and Asp (within the motifs HXXXD and HXH)
66555976675370Water nucleophile; water bound by single zinc ion ligated to two His and Asp (within the motif HSHP(X)9D)
11114Asparagine nucleophile; catalytic residues in the order Asp, Asn in sequence; all self-processing endopeptidases
2412110Serine or cysteine nucleophile; catalytic residues in the order His, Asp, Ser (or Cys) in sequence; all endopeptidases
182023182323202121222018247Threonine, serine or cysteine nucleophile at the N-terminus of mature enzyme
1145231254553564Serine or cysteine nucleophile; catalytic residues in the order Cys (or Ser), His, Glu in sequence.
111115Serine or threonine nucleophile; N-terminal nucleophile
6102911010239163412151Serine nucleophile; catalytic residues in the order Asp, His, Ser in sequence in family S8, but family S53 differs
98105102441027411311413117831401,132Serine nucleophile; catalytic residues in the order Ser, Asp, His in sequence
2121224446147Serine nucleophile; catalytic residues in the order Ser, Lys (within the motif SXXK) in sequence
33325453443241Serine nucleophile; catalytic residues in the order Ser, Lys (or His) in sequence
11Serine nucleophile; catalytic residues in the order Ser, Lys in sequence
1111111111111Serine nucleophile; catalytic residues in the order Ser, His, Asp in sequence
11Serine nucleophile; catalytic residues in the order His, Ser within the motif HXS.
36533645434349Serine nucleophile; transmembrane protein with catalytic residues in the order Ser, His embedded in the membrane
112Families of peptidases of unknown catalytic mechanism not assigned to clans
11111111111112
15521710142117221613913219
11
112
11125