Peptidases • Blastocladiella britannica v1.0
Annotations/GenomesAllma1Batde5Blabri1Catan2Ganpr1Pirfi3Rhihy1Rozal1_1Spipu1TotalAnnotation Description
Merops
4323142162503412283601432102,494
510311612778159Water nucleophile; water bound by two Asp from monomer or dimer; all endopeptidases, from eukaryote organisms, viruses or virus-like organisms
112Water nucleophile; water bound by two Asp; all membrane-bound endopeptidases known only from eubacteria with active site on periplasmic side of cell membrane.
4122233219Water nucleophile; water bound by two Asp; all membrane-bound endopeptidases known only from eubacteria with active site on cytoplasmic side of cell membrane.
431919152120221715191Cysteine nucleophile; catalytic residues in the order Cys, His, Asn (or Asp) in sequence
1438971463367Cysteine nucleophile; catalytic residues in the order His, Cys in sequence
22312142219Cysteine nucleophile; catalytic residues in the order His, Glu (or Asp), Cys in sequence
211111119Cysteine nucleophile; catalytic residues in the order Glu, Cys, His in sequence
112Cysteine nucleophile; catalytic residues in the order His, Cys in sequence
11Cysteine nucleophile; catalytic residues in the order His, Cys in sequence
11Water nucleophile; water bound by Glu; all self-cleaving endopeptidases
10571155114462Families of peptidase inhibitors not assigned to clans
22
11
213
212111210
2111128
112
211144114Families of metallopeptidases not assigned to clans
573522171830251211227Water nucleophile; water bound by single zinc ion ligated to two His (within the motif HEXXH) and Glu, His or Asp
618116262244Water nucleophile; water bound by single zinc ion ligated to His, Glu (within the motif HXXE) and His
12111118Water nucleophile; water bound by single zinc ion ligated to two His (within the motif HXXEH) and Glu
102654352441Water nucleophile; water bound by two zinc ions ligated by Lys, Asp, Asp, Asp, Glu
1678875116977Water nucleophile; water bound by two cobalt or manganese ions ligated by Asp, Asp, His, Glu, Glu
21117916525412110Water nucleophile; water bound by two zinc ions ligated by His (or Asp), Asp, Glu, Asp (or Glu), His
114341319550Water nucleophile; water bound by two zinc ions ligated by His, His or Asp, Lys or Glu, His, His.
11114Water nucleophile; water bound by single zinc ion ligated to two His (within the motif HEXXH) and Asp; membrane proteins with intramembrane active site.
11Water nucleophile; water bound by two zinc ions ligated by Asp, Glu, His, His, Glu
76673551444Water nucleophile; water bound by single zinc ion ligated to two His and Asp (within the motif HSHP(X)9D)
11125Asparagine nucleophile; catalytic residues in the order Asp, Asn in sequence; all self-processing endopeptidases
11Asparagine nucleophile; catalytic residues in the order Asn, Glu in sequence; all self-processing endopeptidases
911311328Serine or cysteine nucleophile; catalytic residues in the order His, Asp, Ser (or Cys) in sequence; all endopeptidases
331519192117191419176Threonine, serine or cysteine nucleophile at the N-terminus of mature enzyme
75335396546Serine or cysteine nucleophile; catalytic residues in the order Cys (or Ser), His, Glu in sequence.
2412110Serine or threonine nucleophile; N-terminal nucleophile
30217514178510144Serine nucleophile; catalytic residues in the order Asp, His, Ser in sequence in family S8, but family S53 differs
8644393611958982349552Serine nucleophile; catalytic residues in the order Ser, Asp, His in sequence
1951613145Serine nucleophile; catalytic residues in the order Ser, Lys (within the motif SXXK) in sequence
115475353750Serine nucleophile; catalytic residues in the order Ser, Lys (or His) in sequence
22Serine nucleophile; catalytic residues in the order Ser, Lys in sequence
51113121217Serine nucleophile; catalytic residues in the order Ser, His, Asp in sequence
93666555449Serine nucleophile; transmembrane protein with catalytic residues in the order Ser, His embedded in the membrane
224Families of peptidases of unknown catalytic mechanism not assigned to clans
3112119
242412121715312115171
22217