Peptidases • Wood Rot Fungi
Annotations/GenomesConpu1Dacsp1Dicsq1Fomme1Fompi3Glotr1_1Hetan2Pospl1Punst1Schco3SerlaS7_9_2Stehi1Trave1Wolco1TotalAnnotation Description
Merops
4322994073163383153041963903453464144333214,856
5930443339363420492961366240572Water nucleophile; water bound by two Asp from monomer or dimer; all endopeptidases, from eukaryote organisms, viruses or virus-like organisms
11Water nucleophile; water bound by two Asp; all membrane-bound endopeptidases known only from eubacteria with active site on periplasmic side of cell membrane.
1311411212121122Water nucleophile; water bound by two Asp; all membrane-bound endopeptidases known only from eubacteria with active site on cytoplasmic side of cell membrane.
251916211420188162022241516254Cysteine nucleophile; catalytic residues in the order Cys, His, Asn (or Asp) in sequence
936510676454104887Cysteine nucleophile; catalytic residues in the order His, Cys in sequence
1231151221221Cysteine nucleophile; catalytic residues in the order His, Glu (or Asp), Cys in sequence
112Cysteine nucleophile; catalytic residues in the order Glu, Cys, His in sequence
11Cysteine nucleophile; catalytic residues in the order Cys, His, His in sequence
11Cysteine nucleophile; catalytic residues in the order His, Cys in sequence
252361116146Water nucleophile; water bound by Gln and Glu; all endopeptidases
2323232232232233Families of peptidase inhibitors not assigned to clans
11
111115
111112221113
213212423718238
2222333423272441Families of metallopeptidases not assigned to clans
175151311151311152211122211193Water nucleophile; water bound by single zinc ion ligated to two His (within the motif HEXXH) and Glu, His or Asp
11121118Water nucleophile; water bound by single zinc ion ligated to His, Glu (within the motif HXXE) and His
121111111111316Water nucleophile; water bound by single zinc ion ligated to two His (within the motif HXXEH) and Glu
211121311Water nucleophile; water bound by two zinc ions ligated by Lys, Asp, Asp, Asp, Glu
710811799481081499123Water nucleophile; water bound by two cobalt or manganese ions ligated by Asp, Asp, His, Glu, Glu
221813131616133192315271517230Water nucleophile; water bound by two zinc ions ligated by His (or Asp), Asp, Glu, Asp (or Glu), His
17121581111148111215151212173Water nucleophile; water bound by two zinc ions ligated by His, His or Asp, Lys or Glu, His, His.
11111111111112Water nucleophile; water bound by single zinc ion ligated to two His (within the motif HEXXH) and Asp; membrane proteins with intramembrane active site.
11Water nucleophile; water bound by single zinc ion ligated to two His and Asp (within the motifs HXXXD and HXH)
6567565165667677Water nucleophile; water bound by single zinc ion ligated to two His and Asp (within the motif HSHP(X)9D)
111115Asparagine nucleophile; catalytic residues in the order Asp, Asn in sequence; all self-processing endopeptidases
11Asparagine nucleophile; all self-processing endopeptidases
111216Serine or cysteine nucleophile; catalytic residues in the order His, Asp, Ser (or Cys) in sequence; all endopeptidases
182322202222228212221212224288Threonine, serine or cysteine nucleophile at the N-terminus of mature enzyme
10377464367455576Serine or cysteine nucleophile; catalytic residues in the order Cys (or Ser), His, Glu in sequence.
213Serine or threonine nucleophile; N-terminal nucleophile
1910328281119101269193420237Serine nucleophile; catalytic residues in the order Asp, His, Ser in sequence in family S8, but family S53 differs
13410213611611611296751451321141461781051,707Serine nucleophile; catalytic residues in the order Ser, Asp, His in sequence
512516425834106172Serine nucleophile; catalytic residues in the order Ser, Lys (within the motif SXXK) in sequence
5544333633334453Serine nucleophile; catalytic residues in the order Ser, Lys (or His) in sequence
1111111111111114Serine nucleophile; catalytic residues in the order Ser, His, Asp in sequence
112Serine nucleophile; catalytic residues in the order His, Ser within the motif HXS.
4353435434543353Serine nucleophile; transmembrane protein with catalytic residues in the order Ser, His embedded in the membrane
111115Families of peptidases of unknown catalytic mechanism not assigned to clans
111111111111113
3214523116141611481222231322326
11
112
11
213129