Peptidases • Russula compacta BPL669 v1.0
Annotations/GenomesAurvu1Clapy1Densp1Glocon1Hetan2Lacqui1Lacsub1Lacvol1Lenvul1Lopni1Muloch1Ricme1Rusbre1Ruscom1Rusdis1Rusrug1Stehi1Varmin1TotalAnnotation Description
Merops
3883724003333047032513043294182954402532132273174143386,299
563784203451233433423251201823373630661Water nucleophile; water bound by two Asp from monomer or dimer; all endopeptidases, from eukaryote organisms, viruses or virus-like organisms
11111212221111112123Water nucleophile; water bound by two Asp; all membrane-bound endopeptidases known only from eubacteria with active site on cytoplasmic side of cell membrane.
161221151826121310251324111113702420354Cysteine nucleophile; catalytic residues in the order Cys, His, Asn (or Asp) in sequence
87537116391561017129121025175Cysteine nucleophile; catalytic residues in the order His, Cys in sequence
11251113141111226Cysteine nucleophile; catalytic residues in the order His, Glu (or Asp), Cys in sequence
11Cysteine nucleophile; catalytic residues in the order Glu, Cys, His in sequence
11Cysteine nucleophile; catalytic residues in the order Cys, His, His in sequence
8412776347Water nucleophile; water bound by Gln and Glu; all endopeptidases
23222122232322223239Families of peptidase inhibitors not assigned to clans
11
11
1111111119
1111112111112116
77464222842561148780
22233322314122227245Families of metallopeptidases not assigned to clans
221813181314202117152219121918161215304Water nucleophile; water bound by single zinc ion ligated to two His (within the motif HEXXH) and Glu, His or Asp
1113Water nucleophile; water bound by single zinc ion ligated to His, Glu (within the motif HXXE) and His
1111121111112221121Water nucleophile; water bound by single zinc ion ligated to two His (within the motif HXXEH) and Glu
11111111111112Water nucleophile; water bound by two zinc ions ligated by Lys, Asp, Asp, Asp, Glu
7788912811812101187771411165Water nucleophile; water bound by two cobalt or manganese ions ligated by Asp, Asp, His, Glu, Glu
141613151312131213221225810792713254Water nucleophile; water bound by two zinc ions ligated by His (or Asp), Asp, Glu, Asp (or Glu), His
99109141191010131213881091510189Water nucleophile; water bound by two zinc ions ligated by His, His or Asp, Lys or Glu, His, His.
121111111111111117Water nucleophile; water bound by single zinc ion ligated to two His (within the motif HEXXH) and Asp; membrane proteins with intramembrane active site.
11237Water nucleophile; water bound by single zinc ion ligated to two His and Asp (within the motifs HXXXD and HXH)
755756655675666666105Water nucleophile; water bound by single zinc ion ligated to two His and Asp (within the motif HSHP(X)9D)
111115Asparagine nucleophile; catalytic residues in the order Asp, Asn in sequence; all self-processing endopeptidases
111115Serine or cysteine nucleophile; catalytic residues in the order His, Asp, Ser (or Cys) in sequence; all endopeptidases
252020202220213720212024191820182120386Threonine, serine or cysteine nucleophile at the N-terminus of mature enzyme
874644554851143335493Serine or cysteine nucleophile; catalytic residues in the order Cys (or Ser), His, Glu in sequence.
2114Serine or threonine nucleophile; N-terminal nucleophile
3632422619367814211830171069101914698Serine nucleophile; catalytic residues in the order Asp, His, Ser in sequence in family S8, but family S53 differs
12114612613396132839811715790162846467761461202,018Serine nucleophile; catalytic residues in the order Ser, Asp, His in sequence
273521423717612310268Serine nucleophile; catalytic residues in the order Ser, Lys (within the motif SXXK) in sequence
44383344232424543365Serine nucleophile; catalytic residues in the order Ser, Lys (or His) in sequence
2911Serine nucleophile; catalytic residues in the order Ser, Lys in sequence
11111111111111111219Serine nucleophile; catalytic residues in the order Ser, His, Asp in sequence
11Serine nucleophile; catalytic residues in the order His, Ser within the motif HXS.
35835434425334424470Serine nucleophile; transmembrane protein with catalytic residues in the order Ser, His embedded in the membrane
112Families of peptidases of unknown catalytic mechanism not assigned to clans
11121111111111111119
19141617161210141722112312910102315270
11114
2215