Peptidases • Exophiala mesophila CBS40295
Annotations/GenomesExoaq1Exode1Exome1Exool1Exosi1Exosp1Exoxe1Phach1TotalAnnotation Description
Merops
5132373074733544214232332,961
12992013151012100Water nucleophile; water bound by two Asp from monomer or dimer; all endopeptidases, from eukaryote organisms, viruses or virus-like organisms
31221110Water nucleophile; water bound by two Asp; all membrane-bound endopeptidases known only from eubacteria with active site on periplasmic side of cell membrane.
1358147915374Water nucleophile; water bound by two Asp; all membrane-bound endopeptidases known only from eubacteria with active site on cytoplasmic side of cell membrane.
2422253123303022207Cysteine nucleophile; catalytic residues in the order Cys, His, Asn (or Asp) in sequence
3264545231Cysteine nucleophile; catalytic residues in the order His, Cys in sequence
11421514Cysteine nucleophile; catalytic residues in the order His, Glu (or Asp), Cys in sequence
112Cysteine nucleophile; catalytic residues in the order Glu, Cys, His in sequence
1111111310Water nucleophile; water bound by Gln and Glu; all endopeptidases
5455445335Families of peptidase inhibitors not assigned to clans
112
112111119
4236364230
4234123322Families of metallopeptidases not assigned to clans
16111014814151199Water nucleophile; water bound by single zinc ion ligated to two His (within the motif HEXXH) and Glu, His or Asp
313111111Water nucleophile; water bound by single zinc ion ligated to His, Glu (within the motif HXXE) and His
2111211211Water nucleophile; water bound by single zinc ion ligated to two His (within the motif HXXEH) and Glu
11Water nucleophile; water bound by two zinc ions ligated by Lys, Asp, Asp, Asp, Glu
66871079861Water nucleophile; water bound by two cobalt or manganese ions ligated by Asp, Asp, His, Glu, Glu
2613192222192717165Water nucleophile; water bound by two zinc ions ligated by His (or Asp), Asp, Glu, Asp (or Glu), His
3713223424262420200Water nucleophile; water bound by two zinc ions ligated by His, His or Asp, Lys or Glu, His, His.
3334543328Water nucleophile; water bound by single zinc ion ligated to two His and Asp (within the motif HSHP(X)9D)
11Water nucleophile; water bound by single zinc ion ligated to Asp, His and His.
311122111Serine or cysteine nucleophile; catalytic residues in the order His, Asp, Ser (or Cys) in sequence; all endopeptidases
2824293530272916218Threonine, serine or cysteine nucleophile at the N-terminus of mature enzyme
92375104242Serine or cysteine nucleophile; catalytic residues in the order Cys (or Ser), His, Glu in sequence.
1124Serine or threonine nucleophile; N-terminal nucleophile
4243356734Serine nucleophile; catalytic residues in the order Asp, His, Ser in sequence in family S8, but family S53 differs
24687107204146197185691,241Serine nucleophile; catalytic residues in the order Ser, Asp, His in sequence
3259221615163118Serine nucleophile; catalytic residues in the order Ser, Lys (within the motif SXXK) in sequence
221122212Serine nucleophile; catalytic residues in the order Ser, Lys (or His) in sequence
2222322217Serine nucleophile; catalytic residues in the order Ser, His, Asp in sequence
3132211114Serine nucleophile; transmembrane protein with catalytic residues in the order Ser, His embedded in the membrane
2114Families of peptidases of unknown catalytic mechanism not assigned to clans
1123111111
8981198101073
121116
112
11
5266324230