Peptidases • Entophlyctis helioformis JEL805 v1.0
Annotations/GenomesBatde5Catan2Chytri1Enthel1Gaesem1Ganpr1Glopol1Neosp1Rhihy1Spipu1TotalAnnotation Description
Merops
3142503552102073413724433602103,062
1031271446272278219Water nucleophile; water bound by two Asp from monomer or dimer; all endopeptidases, from eukaryote organisms, viruses or virus-like organisms
112Water nucleophile; water bound by two Asp; all membrane-bound endopeptidases known only from eubacteria with active site on periplasmic side of cell membrane.
25132243224Water nucleophile; water bound by two Asp; all membrane-bound endopeptidases known only from eubacteria with active site on cytoplasmic side of cell membrane.
19152714152117302215195Cysteine nucleophile; catalytic residues in the order Cys, His, Asn (or Asp) in sequence
3964475216368Cysteine nucleophile; catalytic residues in the order His, Cys in sequence
213322234224Cysteine nucleophile; catalytic residues in the order His, Glu (or Asp), Cys in sequence
111111118Cysteine nucleophile; catalytic residues in the order Glu, Cys, His in sequence
11Cysteine nucleophile; catalytic residues in the order His, Cys in sequence
11Cysteine nucleophile; catalytic residues in the order Cys, His, His in sequence
11Cysteine nucleophile; catalytic residues in the order His, Cys in sequence
112Water nucleophile; water bound by Glu; all self-cleaving endopeptidases
511664572411483Families of peptidase inhibitors not assigned to clans
21315
11
112
11
1131111211
111227
1113
11
11111418119Families of metallopeptidases not assigned to clans
35173510221849452511267Water nucleophile; water bound by single zinc ion ligated to two His (within the motif HEXXH) and Glu, His or Asp
1113136316237Water nucleophile; water bound by single zinc ion ligated to His, Glu (within the motif HXXE) and His
22111119Water nucleophile; water bound by single zinc ion ligated to two His (within the motif HXXEH) and Glu
254344355439Water nucleophile; water bound by two zinc ions ligated by Lys, Asp, Asp, Asp, Glu
78978771011983Water nucleophile; water bound by two cobalt or manganese ions ligated by Asp, Asp, His, Glu, Glu
11925791618152512147Water nucleophile; water bound by two zinc ions ligated by His (or Asp), Asp, Glu, Asp (or Glu), His
44112413519558Water nucleophile; water bound by two zinc ions ligated by His, His or Asp, Lys or Glu, His, His.
121111119Water nucleophile; water bound by single zinc ion ligated to two His (within the motif HEXXH) and Asp; membrane proteins with intramembrane active site.
11Water nucleophile; water bound by two zinc ions ligated by Asp, Glu, His, His, Glu
674443775451Water nucleophile; water bound by single zinc ion ligated to two His and Asp (within the motif HSHP(X)9D)
1211128Asparagine nucleophile; catalytic residues in the order Asp, Asn in sequence; all self-processing endopeptidases
11Asparagine nucleophile; catalytic residues in the order Asn, Glu in sequence; all self-processing endopeptidases
9113132881367Serine or cysteine nucleophile; catalytic residues in the order His, Asp, Ser (or Cys) in sequence; all endopeptidases
15192717172119311919204Threonine, serine or cysteine nucleophile at the N-terminus of mature enzyme
537435439548Serine or cysteine nucleophile; catalytic residues in the order Cys (or Ser), His, Glu in sequence.
11Cysteine nucleophile at the N-terminus of mature enzyme; catalytic residues in the order Cys, Thr, His
11412110Serine or threonine nucleophile; N-terminal nucleophile
2514584516810113Serine nucleophile; catalytic residues in the order Asp, His, Ser in sequence in family S8, but family S53 differs
44361006441119881259849764Serine nucleophile; catalytic residues in the order Ser, Asp, His in sequence
15513162613171Serine nucleophile; catalytic residues in the order Ser, Lys (within the motif SXXK) in sequence
577565585760Serine nucleophile; catalytic residues in the order Ser, Lys (or His) in sequence
11Serine nucleophile; catalytic residues in the order Ser, Lys in sequence
113113322219Serine nucleophile; catalytic residues in the order Ser, His, Asp in sequence
11Serine nucleophile; catalytic residues in the order Ser, Glu, His
3634765155458Serine nucleophile; transmembrane protein with catalytic residues in the order Ser, His embedded in the membrane
22Families of peptidases of unknown catalytic mechanism not assigned to clans
121141111
24122320211724333115220
12262114