Peptidases • Macroventuria anomochaeta CBS 525.71 v1.0
Annotations/GenomesAaoar1Aplpr1Cerzm1Cocca1CocheC5_3Coclu2Cocmi1Cocsa1Cocvi1Cucbe1Didex1Dotsy1Lenfl1Lopma1Macan1Melpu1Mycgr3Photr1Plesi1Settu1Spofi1TotalAnnotation Description
Merops
4062943513353723413263303473283313024284363484663423413533242507,351
132516222918212222162310211316202215121616388Water nucleophile; water bound by two Asp from monomer or dimer; all endopeptidases, from eukaryote organisms, viruses or virus-like organisms
10531012111010108736845412794158Water nucleophile; water bound by two Asp; all membrane-bound endopeptidases known only from eubacteria with active site on cytoplasmic side of cell membrane.
11Water nucleophile; water bound by two Asp
282230262821242727282827312831312725322221564Cysteine nucleophile; catalytic residues in the order Cys, His, Asn (or Asp) in sequence
42344444444364452544381Cysteine nucleophile; catalytic residues in the order His, Cys in sequence
12311111111121112111227Cysteine nucleophile; catalytic residues in the order His, Glu (or Asp), Cys in sequence
31111112113122221228Cysteine nucleophile; catalytic residues in the order Glu, Cys, His in sequence
1111111119Cysteine nucleophile; catalytic residues in the order Cys, His, His in sequence
11111111111111111111121Cysteine nucleophile; catalytic residues in the order His, Cys in sequence
13235133321323245243156Water nucleophile; water bound by Gln and Glu; all endopeptidases
555555555456454555554102Families of peptidase inhibitors not assigned to clans
11
11111111111211111111122
5533232333466343644375
652565466445854825453102Families of metallopeptidases not assigned to clans
19919121119131113171417161518272815201210335Water nucleophile; water bound by single zinc ion ligated to two His (within the motif HEXXH) and Glu, His or Asp
626777777775638447475123Water nucleophile; water bound by single zinc ion ligated to His, Glu (within the motif HXXE) and His
12111111111111111111223Water nucleophile; water bound by single zinc ion ligated to two His (within the motif HXXEH) and Glu
6596666666775767106766136Water nucleophile; water bound by two cobalt or manganese ions ligated by Asp, Asp, His, Glu, Glu
322025232623212119242523262728331725262219505Water nucleophile; water bound by two zinc ions ligated by His (or Asp), Asp, Glu, Asp (or Glu), His
1910101099811118105131711126912137220Water nucleophile; water bound by two zinc ions ligated by His, His or Asp, Lys or Glu, His, His.
111115Water nucleophile; water bound by single zinc ion ligated to two His and Asp (within the motifs HXXXD and HXH)
43433433334333334333368Water nucleophile; water bound by single zinc ion ligated to two His and Asp (within the motif HSHP(X)9D)
112Water nucleophile; water bound by single zinc ion ligated to Asp, His and His.
22422222222142232323147Serine or cysteine nucleophile; catalytic residues in the order His, Asp, Ser (or Cys) in sequence; all endopeptidases
202424212022212021232020212321222120212119445Threonine, serine or cysteine nucleophile at the N-terminus of mature enzyme
11358999888771088768596159Serine or cysteine nucleophile; catalytic residues in the order Cys (or Ser), His, Glu in sequence.
1121218Cysteine nucleophile at the N-terminus of mature enzyme; catalytic residues in the order Cys, Thr, His
111111111111111111119Serine or threonine nucleophile; N-terminal nucleophile
121015161613131416991013151322161316158284Serine nucleophile; catalytic residues in the order Asp, His, Ser in sequence in family S8, but family S53 differs
15999122114132127118111125117116105172202122177119118127114772,673Serine nucleophile; catalytic residues in the order Ser, Asp, His in sequence
10911756466688171192589724178Serine nucleophile; catalytic residues in the order Ser, Lys (within the motif SXXK) in sequence
34333333322334323333261Serine nucleophile; catalytic residues in the order Ser, Lys (or His) in sequence
22312111121211113112232Serine nucleophile; catalytic residues in the order Ser, His, Asp in sequence
1113Serine nucleophile; catalytic residues in the order Ser, Glu, His
34333434355444443554481Serine nucleophile; transmembrane protein with catalytic residues in the order Ser, His embedded in the membrane
1111127Families of peptidases of unknown catalytic mechanism not assigned to clans
1111111119
121191215101112141011111512132091191211250
1214
4122312321532213239