Peptidases • Bisporella sp. PMI_857 v1.0
Annotations/GenomesAcema1Ascsa1Bissp1Glalo1Lorju1Lorma1Marbr1Melbi2Melva1Phisc1TotalAnnotation Description
Merops
5622945253694124142464956526484,617
34151920353210274341276Water nucleophile; water bound by two Asp from monomer or dimer; all endopeptidases, from eukaryote organisms, viruses or virus-like organisms
1113Water nucleophile; water bound by two Asp; all membrane-bound endopeptidases known only from eubacteria with active site on periplasmic side of cell membrane.
1451159108131317105Water nucleophile; water bound by two Asp; all membrane-bound endopeptidases known only from eubacteria with active site on cytoplasmic side of cell membrane.
29192925212423354026271Cysteine nucleophile; catalytic residues in the order Cys, His, Asn (or Asp) in sequence
433244355437Cysteine nucleophile; catalytic residues in the order His, Cys in sequence
21253121219Cysteine nucleophile; catalytic residues in the order His, Glu (or Asp), Cys in sequence
22212113317Cysteine nucleophile; catalytic residues in the order Glu, Cys, His in sequence
224Cysteine nucleophile; catalytic residues in the order Cys, His, His in sequence
1111116Cysteine nucleophile; catalytic residues in the order His, Cys in sequence
744532615854Water nucleophile; water bound by Gln and Glu; all endopeptidases
444455454544Families of peptidase inhibitors not assigned to clans
11
112
11
11
12122212215
634354338544
7512366277762Families of metallopeptidases not assigned to clans
1693421151416172221185Water nucleophile; water bound by single zinc ion ligated to two His (within the motif HEXXH) and Glu, His or Asp
115211211116Water nucleophile; water bound by single zinc ion ligated to His, Glu (within the motif HXXE) and His
122111222115Water nucleophile; water bound by single zinc ion ligated to two His (within the motif HXXEH) and Glu
10811999410101292Water nucleophile; water bound by two cobalt or manganese ions ligated by Asp, Asp, His, Glu, Glu
34164026272618273241287Water nucleophile; water bound by two zinc ions ligated by His (or Asp), Asp, Glu, Asp (or Glu), His
1912161410119182226157Water nucleophile; water bound by two zinc ions ligated by His, His or Asp, Lys or Glu, His, His.
112Water nucleophile; water bound by single zinc ion ligated to two His and Asp (within the motifs HXXXD and HXH)
443444344438Water nucleophile; water bound by single zinc ion ligated to two His and Asp (within the motif HSHP(X)9D)
11111117Water nucleophile; water bound by single zinc ion ligated to Asp, His and His.
213222344326Serine or cysteine nucleophile; catalytic residues in the order His, Asp, Ser (or Cys) in sequence; all endopeptidases
24212724262521242826246Threonine, serine or cysteine nucleophile at the N-terminus of mature enzyme
6376633511656Serine or cysteine nucleophile; catalytic residues in the order Cys (or Ser), His, Glu in sequence.
411121111Serine or threonine nucleophile; N-terminal nucleophile
11Families of serine peptidases not assigned to clans
35172315222612253434243Serine nucleophile; catalytic residues in the order Asp, His, Ser in sequence in family S8, but family S53 differs
238110204144147157691842862951,834Serine nucleophile; catalytic residues in the order Ser, Asp, His in sequence
1852171592221923141Serine nucleophile; catalytic residues in the order Ser, Lys (within the motif SXXK) in sequence
334333233330Serine nucleophile; catalytic residues in the order Ser, Lys (or His) in sequence
213111121114Serine nucleophile; catalytic residues in the order Ser, His, Asp in sequence
122117Serine nucleophile; catalytic residues in the order Ser, Glu, His
623334465238Serine nucleophile; transmembrane protein with catalytic residues in the order Ser, His embedded in the membrane
111115Families of peptidases of unknown catalytic mechanism not assigned to clans
111111111110
18152013131411231515157
211127
5143344630