Peptidases • Coprinellus pellucidus v1.0
Annotations/GenomesAmath1Copci1Copci_AmutBmut1Copmic2Coppel1Copscl1Guyne1Marfi1Panst_KUC8834_1_1PleosPC9_1TotalAnnotation Description
Merops
3182872923903002883584554653523,505
19112015181228255823229Water nucleophile; water bound by two Asp from monomer or dimer; all endopeptidases, from eukaryote organisms, viruses or virus-like organisms
112Water nucleophile; water bound by two Asp; all membrane-bound endopeptidases known only from eubacteria with active site on periplasmic side of cell membrane.
321131314Water nucleophile; water bound by two Asp; all membrane-bound endopeptidases known only from eubacteria with active site on cytoplasmic side of cell membrane.
55111Water nucleophile; water bound by two Asp
14151421171421242721188Cysteine nucleophile; catalytic residues in the order Cys, His, Asn (or Asp) in sequence
35613952069884Cysteine nucleophile; catalytic residues in the order His, Cys in sequence
11121118Cysteine nucleophile; catalytic residues in the order His, Glu (or Asp), Cys in sequence
112Cysteine nucleophile; catalytic residues in the order Glu, Cys, His in sequence
55Water nucleophile; water bound by Gln and Glu; all endopeptidases
9768353105258Families of peptidase inhibitors not assigned to clans
11
11221111313
555756652652
333112333224Families of metallopeptidases not assigned to clans
36302935372816401931301Water nucleophile; water bound by single zinc ion ligated to two His (within the motif HEXXH) and Glu, His or Asp
1111111310Water nucleophile; water bound by single zinc ion ligated to His, Glu (within the motif HXXE) and His
111111121111Water nucleophile; water bound by single zinc ion ligated to two His (within the motif HXXEH) and Glu
111113121113Water nucleophile; water bound by two zinc ions ligated by Lys, Asp, Asp, Asp, Glu
97891291011101196Water nucleophile; water bound by two cobalt or manganese ions ligated by Asp, Asp, His, Glu, Glu
22222117191913252118197Water nucleophile; water bound by two zinc ions ligated by His (or Asp), Asp, Glu, Asp (or Glu), His
1087111081515189111Water nucleophile; water bound by two zinc ions ligated by His, His or Asp, Lys or Glu, His, His.
1111116Water nucleophile; water bound by single zinc ion ligated to two His (within the motif HEXXH) and Asp; membrane proteins with intramembrane active site.
1131118Water nucleophile; water bound by single zinc ion ligated to two His and Asp (within the motifs HXXXD and HXH)
675755766660Water nucleophile; water bound by single zinc ion ligated to two His and Asp (within the motif HSHP(X)9D)
1214Asparagine nucleophile; catalytic residues in the order Asp, Asn in sequence; all self-processing endopeptidases
1111116Serine or cysteine nucleophile; catalytic residues in the order His, Asp, Ser (or Cys) in sequence; all endopeptidases
20191925211921262320213Threonine, serine or cysteine nucleophile at the N-terminus of mature enzyme
687957675666Serine or cysteine nucleophile; catalytic residues in the order Cys (or Ser), His, Glu in sequence.
11Serine or threonine nucleophile; N-terminal nucleophile
1489208317112912149Serine nucleophile; catalytic residues in the order Asp, His, Ser in sequence in family S8, but family S53 differs
1019910014493851502021781301,282Serine nucleophile; catalytic residues in the order Ser, Asp, His in sequence
1322863458354Serine nucleophile; catalytic residues in the order Ser, Lys (within the motif SXXK) in sequence
323433333330Serine nucleophile; catalytic residues in the order Ser, Lys (or His) in sequence
112Serine nucleophile; catalytic residues in the order Ser, Lys in sequence
111111111110Serine nucleophile; catalytic residues in the order Ser, His, Asp in sequence
11Serine nucleophile; catalytic residues in the order Ser, Glu, His
433334434435Serine nucleophile; transmembrane protein with catalytic residues in the order Ser, His embedded in the membrane
112Families of peptidases of unknown catalytic mechanism not assigned to clans
111111111110
1310915111011131224128
112
66