Peptidases • Fonsecaea monophora CBS 269.37
Annotations/GenomesCapcor1Capep1Capse1Claba1Claca1Claim1Claps1Claye1Exoalc1Exoalc1_J33Exoaq1Exode1Exome1Exool1Exosi1Exosp1Exoxe1Fonmo1Fonmu1Fonpe1TotalAnnotation Description
Merops
2723043664053193924343173823775132373074733544214233634053717,435
811161612181611119129920131510131314256Water nucleophile; water bound by two Asp from monomer or dimer; all endopeptidases, from eukaryote organisms, viruses or virus-like organisms
1111111223122111123Water nucleophile; water bound by two Asp; all membrane-bound endopeptidases known only from eubacteria with active site on periplasmic side of cell membrane.
64129711158111013581479158118191Water nucleophile; water bound by two Asp; all membrane-bound endopeptidases known only from eubacteria with active site on cytoplasmic side of cell membrane.
2223242923312827252624222531233030242324514Cysteine nucleophile; catalytic residues in the order Cys, His, Asn (or Asp) in sequence
2335334433326454533371Cysteine nucleophile; catalytic residues in the order His, Cys in sequence
1311111421511124Cysteine nucleophile; catalytic residues in the order His, Glu (or Asp), Cys in sequence
1111116Cysteine nucleophile; catalytic residues in the order Glu, Cys, His in sequence
4111111111111117Water nucleophile; water bound by Gln and Glu; all endopeptidases
11Water nucleophile; water bound by Glu; all self-cleaving endopeptidases
5655455455545544545595Families of peptidase inhibitors not assigned to clans
112
1111111211112111111122
4446376366423636467696
2333275232423412324461Families of metallopeptidases not assigned to clans
91113111111111213121611101481415699226Water nucleophile; water bound by single zinc ion ligated to two His (within the motif HEXXH) and Glu, His or Asp
111313111114Water nucleophile; water bound by single zinc ion ligated to His, Glu (within the motif HXXE) and His
1111111111211121111122Water nucleophile; water bound by single zinc ion ligated to two His (within the motif HXXEH) and Glu
578678677766871079677141Water nucleophile; water bound by two cobalt or manganese ions ligated by Asp, Asp, His, Glu, Glu
2025212217262216211926131922221927261825426Water nucleophile; water bound by two zinc ions ligated by His (or Asp), Asp, Glu, Asp (or Glu), His
2222252724183122292937132234242624262725507Water nucleophile; water bound by two zinc ions ligated by His, His or Asp, Lys or Glu, His, His.
3333453333333454334368Water nucleophile; water bound by single zinc ion ligated to two His and Asp (within the motif HSHP(X)9D)
11211111110Water nucleophile; water bound by single zinc ion ligated to Asp, His and His.
1312111131112211124Serine or cysteine nucleophile; catalytic residues in the order His, Asp, Ser (or Cys) in sequence; all endopeptidases
3125212421232422282828242935302729222226519Threonine, serine or cysteine nucleophile at the N-terminus of mature enzyme
34332332349237510444482Serine or cysteine nucleophile; catalytic residues in the order Cys (or Ser), His, Glu in sequence.
1111111119Serine or threonine nucleophile; N-terminal nucleophile
4475488633424335676698Serine nucleophile; catalytic residues in the order Asp, His, Ser in sequence in family S8, but family S53 differs
95105161189139161204132171170246871072041461971851611951633,218Serine nucleophile; catalytic residues in the order Ser, Asp, His in sequence
6119127151271313325922161516161413263Serine nucleophile; catalytic residues in the order Ser, Lys (within the motif SXXK) in sequence
2222222222221122222238Serine nucleophile; catalytic residues in the order Ser, Lys (or His) in sequence
1233322322222232222244Serine nucleophile; catalytic residues in the order Ser, His, Asp in sequence
11Serine nucleophile; catalytic residues in the order Ser, Glu, His
2312223233313221123344Serine nucleophile; transmembrane protein with catalytic residues in the order Ser, His embedded in the membrane
112221111113Families of peptidases of unknown catalytic mechanism not assigned to clans
1111111111112311111123
888810889910898119810797172
111211119
112
11
4764435432526632437282