Peptidases • Wickerhamiella domercqiae NRRL Y-6692 v1.0
Annotations/GenomesArxad1Sugame1Symat1Tripe1Wicdo1Zyghe1_2TotalAnnotation Description
Merops
2062002081901571841,145
211924191014107Water nucleophile; water bound by two Asp from monomer or dimer; all endopeptidases, from eukaryote organisms, viruses or virus-like organisms
213Water nucleophile; water bound by two Asp; all membrane-bound endopeptidases known only from eubacteria with active site on periplasmic side of cell membrane.
122128Water nucleophile; water bound by two Asp; all membrane-bound endopeptidases known only from eubacteria with active site on cytoplasmic side of cell membrane.
211220171618104Cysteine nucleophile; catalytic residues in the order Cys, His, Asn (or Asp) in sequence
23332215Cysteine nucleophile; catalytic residues in the order His, Cys in sequence
12115Cysteine nucleophile; catalytic residues in the order His, Glu (or Asp), Cys in sequence
1111116Cysteine nucleophile; catalytic residues in the order His, Cys in sequence
34643323Families of peptidase inhibitors not assigned to clans
112
212128
23222213
122117Families of metallopeptidases not assigned to clans
10131112101369Water nucleophile; water bound by single zinc ion ligated to two His (within the motif HEXXH) and Glu, His or Asp
1113Water nucleophile; water bound by single zinc ion ligated to His, Glu (within the motif HXXE) and His
22132111Water nucleophile; water bound by single zinc ion ligated to two His (within the motif HXXEH) and Glu
86976743Water nucleophile; water bound by two cobalt or manganese ions ligated by Asp, Asp, His, Glu, Glu
17141413141991Water nucleophile; water bound by two zinc ions ligated by His (or Asp), Asp, Glu, Asp (or Glu), His
44546730Water nucleophile; water bound by two zinc ions ligated by His, His or Asp, Lys or Glu, His, His.
45554326Water nucleophile; water bound by single zinc ion ligated to two His and Asp (within the motif HSHP(X)9D)
11Asparagine nucleophile; catalytic residues in the order Asp, Asn in sequence; all self-processing endopeptidases
112Serine or cysteine nucleophile; catalytic residues in the order His, Asp, Ser (or Cys) in sequence; all endopeptidases
212018192117116Threonine, serine or cysteine nucleophile at the N-terminus of mature enzyme
53233420Serine or cysteine nucleophile; catalytic residues in the order Cys (or Ser), His, Glu in sequence.
22Cysteine nucleophile at the N-terminus of mature enzyme; catalytic residues in the order Cys, Thr, His
111115Serine or threonine nucleophile; N-terminal nucleophile
44543424Serine nucleophile; catalytic residues in the order Asp, His, Ser in sequence in family S8, but family S53 differs
515448462937265Serine nucleophile; catalytic residues in the order Ser, Asp, His in sequence
224Serine nucleophile; catalytic residues in the order Ser, Lys (within the motif SXXK) in sequence
33333318Serine nucleophile; catalytic residues in the order Ser, Lys (or His) in sequence
11Serine nucleophile; catalytic residues in the order Ser, Lys in sequence
22Serine nucleophile; catalytic residues in the order Ser, His, Asp in sequence
11Serine nucleophile; catalytic residues in the order His, Ser within the motif HXS.
24643625Serine nucleophile; transmembrane protein with catalytic residues in the order Ser, His embedded in the membrane
112Families of peptidases of unknown catalytic mechanism not assigned to clans
1111116
13121313111274
11
11
11