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Peptidases • Issatchenkia orientalis SD108 v2.0
Annotations/GenomesCanar1Dekbr2Hanpo2Isori2Issori2Issorie2Ogapa1Picme2TotalAnnotation Description
Merops
1411431511371441401551341,145
126581085660Water nucleophile; water bound by two Asp from monomer or dimer; all endopeptidases, from eukaryote organisms, viruses or virus-like organisms
111115Water nucleophile; water bound by two Asp; all membrane-bound endopeptidases known only from eubacteria with active site on cytoplasmic side of cell membrane.
1215141516151413114Cysteine nucleophile; catalytic residues in the order Cys, His, Asn (or Asp) in sequence
2332222218Cysteine nucleophile; catalytic residues in the order His, Cys in sequence
1121117Cysteine nucleophile; catalytic residues in the order His, Glu (or Asp), Cys in sequence
2114Water nucleophile; water bound by Gln and Glu; all endopeptidases
3342224222Families of peptidase inhibitors not assigned to clans
11111117
11114
2221112213
11111117Families of metallopeptidases not assigned to clans
8666766651Water nucleophile; water bound by single zinc ion ligated to two His (within the motif HEXXH) and Glu, His or Asp
111111118Water nucleophile; water bound by single zinc ion ligated to His, Glu (within the motif HXXE) and His
2121222113Water nucleophile; water bound by single zinc ion ligated to two His (within the motif HXXEH) and Glu
6788888861Water nucleophile; water bound by two cobalt or manganese ions ligated by Asp, Asp, His, Glu, Glu
101413101112131194Water nucleophile; water bound by two zinc ions ligated by His (or Asp), Asp, Glu, Asp (or Glu), His
6996668757Water nucleophile; water bound by two zinc ions ligated by His, His or Asp, Lys or Glu, His, His.
4433334529Water nucleophile; water bound by single zinc ion ligated to two His and Asp (within the motif HSHP(X)9D)
11Serine or cysteine nucleophile; catalytic residues in the order His, Asp, Ser (or Cys) in sequence; all endopeptidases
1618181819181919145Threonine, serine or cysteine nucleophile at the N-terminus of mature enzyme
3133434324Serine or cysteine nucleophile; catalytic residues in the order Cys (or Ser), His, Glu in sequence.
111111118Serine or threonine nucleophile; N-terminal nucleophile
3333223322Serine nucleophile; catalytic residues in the order Asp, His, Ser in sequence in family S8, but family S53 differs
3027332628283424230Serine nucleophile; catalytic residues in the order Ser, Asp, His in sequence
112Serine nucleophile; catalytic residues in the order Ser, Lys (within the motif SXXK) in sequence
3333333324Serine nucleophile; catalytic residues in the order Ser, Lys (or His) in sequence
11Serine nucleophile; catalytic residues in the order His, Ser within the motif HXS.
3423343224Serine nucleophile; transmembrane protein with catalytic residues in the order Ser, His embedded in the membrane
221117Families of peptidases of unknown catalytic mechanism not assigned to clans
111211119
6119810910871
123