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Peptidases • Coccomyces strobi CBS 202.91 v1.0
Annotations/GenomesAcema1Amore1Cadsp1Chalo1Cocst1Lorju1Melbi2Melva1Oidma1Phisc1Rhier1Rutfi1Themi1TotalAnnotation Description
Merops
5622567256723154124956526226484193421756,295
3415315016352743364132167383Water nucleophile; water bound by two Asp from monomer or dimer; all endopeptidases, from eukaryote organisms, viruses or virus-like organisms
11114Water nucleophile; water bound by two Asp; all membrane-bound endopeptidases known only from eubacteria with active site on periplasmic side of cell membrane.
14717165913131117753137Water nucleophile; water bound by two Asp; all membrane-bound endopeptidases known only from eubacteria with active site on cytoplasmic side of cell membrane.
29203729242135403326302419367Cysteine nucleophile; catalytic residues in the order Cys, His, Asn (or Asp) in sequence
443534554452250Cysteine nucleophile; catalytic residues in the order His, Cys in sequence
211325211231226Cysteine nucleophile; catalytic residues in the order His, Glu (or Asp), Cys in sequence
215311131312125Cysteine nucleophile; catalytic residues in the order Glu, Cys, His in sequence
1113Cysteine nucleophile; catalytic residues in the order Cys, His, His in sequence
1111111111111Cysteine nucleophile; catalytic residues in the order His, Cys in sequence
72418456151387594Water nucleophile; water bound by Gln and Glu; all endopeptidases
112Water nucleophile; water bound by Glu; all self-cleaving endopeptidases
455445545544559Families of peptidase inhibitors not assigned to clans
112
111216
22
22
12112212122219
637765386523162
11
7410846778733175Families of metallopeptidases not assigned to clans
16933238151722152112119211Water nucleophile; water bound by single zinc ion ligated to two His (within the motif HEXXH) and Glu, His or Asp
112111111112115Water nucleophile; water bound by single zinc ion ligated to His, Glu (within the motif HXXE) and His
111211221121117Water nucleophile; water bound by single zinc ion ligated to two His (within the motif HXXEH) and Glu
10811108910101012986121Water nucleophile; water bound by two cobalt or manganese ions ligated by Asp, Asp, His, Glu, Glu
3418413823272732304120239363Water nucleophile; water bound by two zinc ions ligated by His (or Asp), Asp, Glu, Asp (or Glu), His
1911252312101822182611115211Water nucleophile; water bound by two zinc ions ligated by His, His or Asp, Lys or Glu, His, His.
11Water nucleophile; water bound by single zinc ion ligated to two His and Asp (within the motifs HXXXD and HXH)
444444444444351Water nucleophile; water bound by single zinc ion ligated to two His and Asp (within the motif HSHP(X)9D)
1111111119Water nucleophile; water bound by single zinc ion ligated to Asp, His and His.
274244232232Serine or cysteine nucleophile; catalytic residues in the order His, Asp, Ser (or Cys) in sequence; all endopeptidases
24222727222624282926252022322Threonine, serine or cysteine nucleophile at the N-terminus of mature enzyme
621311465118644484Serine or cysteine nucleophile; catalytic residues in the order Cys (or Ser), His, Glu in sequence.
4211121211117Serine or threonine nucleophile; N-terminal nucleophile
112Families of serine peptidases not assigned to clans
3513403518222534383425145338Serine nucleophile; catalytic residues in the order Asp, His, Ser in sequence in family S8, but family S53 differs
23875315290106147184286274295160144412,555Serine nucleophile; catalytic residues in the order Ser, Asp, His in sequence
18430211015221926231391211Serine nucleophile; catalytic residues in the order Ser, Lys (within the motif SXXK) in sequence
333333333333339Serine nucleophile; catalytic residues in the order Ser, Lys (or His) in sequence
211211213121119Serine nucleophile; catalytic residues in the order Ser, His, Asp in sequence
112116Serine nucleophile; catalytic residues in the order Ser, Glu, His
633533652233145Serine nucleophile; transmembrane protein with catalytic residues in the order Ser, His embedded in the membrane
11114Families of peptidases of unknown catalytic mechanism not assigned to clans
111111111111113
18123014141323152415171217224
2211112111
524613445621144