Peptidases • Sporodiniella umbellata MES 1446 v1.0
Annotations/GenomesBacci1Blatri1Cokrec1Gilper1Kircor1Mucci2Mycafr1Parpar1Pilano1Pilumb1Rhich1Rhimi1_1Rhimi_ATCC52814_1Rhior3Spoumb1Thaele1Zyghet1TotalAnnotation Description
Merops
4222512472643673042332652612403762532322902552943024,856
3118212436241619191635202033322331418Water nucleophile; water bound by two Asp from monomer or dimer; all endopeptidases, from eukaryote organisms, viruses or virus-like organisms
11Water nucleophile; water bound by two Asp; all membrane-bound endopeptidases known only from eubacteria with active site on periplasmic side of cell membrane.
10333443343544444469Water nucleophile; water bound by two Asp; all membrane-bound endopeptidases known only from eubacteria with active site on cytoplasmic side of cell membrane.
4026222636352330302845292828243431515Cysteine nucleophile; catalytic residues in the order Cys, His, Asn (or Asp) in sequence
6566666556866456597Cysteine nucleophile; catalytic residues in the order His, Cys in sequence
1632332224232114252Cysteine nucleophile; catalytic residues in the order His, Glu (or Asp), Cys in sequence
11211111111113Cysteine nucleophile; catalytic residues in the order Cys, His, His in sequence
2122211121211222227Cysteine nucleophile; catalytic residues in the order His, Cys in sequence
9376973776127713577122Families of peptidase inhibitors not assigned to clans
111111211111
11211118
11114
813122
121211111221211121
5212522333111212440
1111111121111115Families of metallopeptidases not assigned to clans
2623171719231520201928181518182624346Water nucleophile; water bound by single zinc ion ligated to two His (within the motif HEXXH) and Glu, His or Asp
311141112Water nucleophile; water bound by single zinc ion ligated to two His (within the motif HXXEH) and Glu
4444444444844444674Water nucleophile; water bound by two zinc ions ligated by Lys, Asp, Asp, Asp, Glu
15119121213121212121614121391212208Water nucleophile; water bound by two cobalt or manganese ions ligated by Asp, Asp, His, Glu, Glu
16788151191010814111016121012187Water nucleophile; water bound by two zinc ions ligated by His (or Asp), Asp, Glu, Asp (or Glu), His
1155781277765644676113Water nucleophile; water bound by two zinc ions ligated by His, His or Asp, Lys or Glu, His, His.
1121321111211112224Water nucleophile; water bound by single zinc ion ligated to two His (within the motif HEXXH) and Asp; membrane proteins with intramembrane active site.
74457645551066646595Water nucleophile; water bound by single zinc ion ligated to two His and Asp (within the motif HSHP(X)9D)
112Asparagine nucleophile; catalytic residues in the order Asp, Asn in sequence; all self-processing endopeptidases
3223312322211112132Serine or cysteine nucleophile; catalytic residues in the order His, Asp, Ser (or Cys) in sequence; all endopeptidases
3518211636231921191931171932232025394Threonine, serine or cysteine nucleophile at the N-terminus of mature enzyme
44431033343532324464Serine or cysteine nucleophile; catalytic residues in the order Cys (or Ser), His, Glu in sequence.
111115Serine or threonine nucleophile; N-terminal nucleophile
221591112108117111511818111114204Serine nucleophile; catalytic residues in the order Asp, His, Ser in sequence in family S8, but family S53 differs
96506051926749615748704648535767691,041Serine nucleophile; catalytic residues in the order Ser, Asp, His in sequence
111211112211116Serine nucleophile; catalytic residues in the order Ser, Lys (within the motif SXXK) in sequence
7434555773765247889Serine nucleophile; catalytic residues in the order Ser, Lys (or His) in sequence
314Serine nucleophile; catalytic residues in the order Ser, Lys in sequence
2211132111112111123Serine nucleophile; catalytic residues in the order Ser, His, Asp in sequence
11156876456964445596Serine nucleophile; transmembrane protein with catalytic residues in the order Ser, His embedded in the membrane
1121117Families of peptidases of unknown catalytic mechanism not assigned to clans
211131111121111120
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