Peptidases • Pucciniomycotina
Annotations/GenomesAgahy1Atrsp2Chiap1Chicu1Croqu1Eryha1Hetpy1Hyabl1Leucr1MecolCla_1Melame1Melap1finSC_191Melli1Mellp2_3Melme_tre1Melmed1Mereb1Micld1Mixos1Naifl1Naose1Pgt_201_A1Pgt_201_B1Pgt_Ug99_A1Pgt_Ug99_C1Phapa1Phlfa1PuccoNC29_1PuccoSD80_1Pucgr2Pucst1Pucst_PST78_1Pucstr1Puctr1Rhoba1_1Rhodia1_1RhodotJ31_1Rhoglu1Rhoglu91_1Rhomi1Rhomuc1Rhosp1Rhoto1Rhoto_ATCC26217_1Rhoto_IFO0559_1Rhoto_IFO0880_2Rhoto_IFO0880_4Rhoto_IFO1236_1Sepsp1Slopil1Spogra1_1Spoli1Spopa1Sporo1Trisp1TotalAnnotation Description
Merops
17842519718919223217218123042020826117823125625929119018330321019219820321535828833830519422424437120818516916318017918716916518317217717618517525332122621418015817412,315
1133191127131212144124273926252830163035231414161529325843131421291410689914891191110121233371325151171,087Water nucleophile; water bound by two Asp from monomer or dimer; all endopeptidases, from eukaryote organisms, viruses or virus-like organisms
111112119Water nucleophile; water bound by two Asp; all membrane-bound endopeptidases known only from eubacteria with active site on periplasmic side of cell membrane.
241151122211112221211111222222123232233223223331333221107Water nucleophile; water bound by two Asp; all membrane-bound endopeptidases known only from eubacteria with active site on cytoplasmic side of cell membrane.
202418161918222120472534142431251911112120181817131814222013221634192017151620131715161415191819202217241416171,068Cysteine nucleophile; catalytic residues in the order Cys, His, Asn (or Asp) in sequence
3732223325173246322422434243523353222223222222222322222155Cysteine nucleophile; catalytic residues in the order His, Cys in sequence
11421224225231411112112111111162Cysteine nucleophile; catalytic residues in the order His, Glu (or Asp), Cys in sequence
111111111112111121111222212111111111111111113155Cysteine nucleophile; catalytic residues in the order Glu, Cys, His in sequence
11191111126Cysteine nucleophile; catalytic residues in the order His, Cys in sequence
3233322223242322322242422425522253322222322122223323333142Families of peptidase inhibitors not assigned to clans
213
112
1113
1111111111111215
1111127
112111111112311120
210312322211463668621315554737853478322221223133324655211210
123
13121111121111121111111112211122222211111155Families of metallopeptidases not assigned to clans
102598566891268109971013712108997101113159111717810786696765656711129881016511Water nucleophile; water bound by single zinc ion ligated to two His (within the motif HEXXH) and Glu, His or Asp
21111111111111121111224Water nucleophile; water bound by single zinc ion ligated to His, Glu (within the motif HXXE) and His
1511111122182133411343Water nucleophile; water bound by single zinc ion ligated to two His (within the motif HXXEH) and Glu
1111111111111123112111214116122121111111111111111111169Water nucleophile; water bound by two zinc ions ligated by Lys, Asp, Asp, Asp, Glu
6146766777117647898746755658688579146777776677777776866775383Water nucleophile; water bound by two cobalt or manganese ions ligated by Asp, Asp, His, Glu, Glu
8271010714881615984988131161210811891014181310141223911139131013991313111014971499995599Water nucleophile; water bound by two zinc ions ligated by His (or Asp), Asp, Glu, Asp (or Glu), His
5146551166141355546513954785992110101089912610101011108910131214101110591141085479Water nucleophile; water bound by two zinc ions ligated by His, His or Asp, Lys or Glu, His, His.
111111111211111111111111212211141111111111111153Water nucleophile; water bound by single zinc ion ligated to two His (within the motif HEXXH) and Asp; membrane proteins with intramembrane active site.
11Water nucleophile; water bound by single zinc ion ligated to two His and Asp (within the motifs HXXXD and HXH)
685556465158776885547565668599557105766665655654555663655334Water nucleophile; water bound by single zinc ion ligated to two His and Asp (within the motif HSHP(X)9D)
1111111111111Asparagine nucleophile; catalytic residues in the order Asp, Asn in sequence; all self-processing endopeptidases
111111118Serine or cysteine nucleophile; catalytic residues in the order His, Asp, Ser (or Cys) in sequence; all endopeptidases
192517182319181918371921171724212419172118181820244720372919263039221820181718202017191819191918202121212118171,179Threonine, serine or cysteine nucleophile at the N-terminus of mature enzyme
31123122242241211433813322372212123222222222322223525231145Serine or cysteine nucleophile; catalytic residues in the order Cys (or Ser), His, Glu in sequence.
311111221121111121Serine or threonine nucleophile; N-terminal nucleophile
29467333416595812824841413131317122202014161221121111121113111151224213394Serine nucleophile; catalytic residues in the order Asp, His, Ser in sequence in family S8, but family S53 differs
46154536354864449711376388437779881055960906761556264901037978565262975647444352505645424945494850488912177614333433,626Serine nucleophile; catalytic residues in the order Ser, Asp, His in sequence
2613622882111211314432444322411673315132Serine nucleophile; catalytic residues in the order Ser, Lys (within the motif SXXK) in sequence
3633343344333333432431424313352246534333433323323343544180Serine nucleophile; catalytic residues in the order Ser, Lys (or His) in sequence
11612112Serine nucleophile; catalytic residues in the order Ser, Lys in sequence
22111221211211211122113312221112222222222212221279Serine nucleophile; catalytic residues in the order Ser, His, Asp in sequence
1113Serine nucleophile; catalytic residues in the order His, Ser within the motif HXS.
344424224321112142421111214331112422334133333332343122131Serine nucleophile; transmembrane protein with catalytic residues in the order Ser, His embedded in the membrane
11114Families of peptidases of unknown catalytic mechanism not assigned to clans
11111111121111111111121211112111111111111111111111155
12201491112131210281512915131713119121512151217301120191618152618111011121312111412121214111421151414101411779
112
2113119
11
12111231112319