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Peptidases • Agaricus bisporus var. burnettii JB137-S8
Annotations/GenomesAgabi_varbisH97_2Agabi_varbur_1Cryne_H99_1Hetan1Lacbi1Malgl1Mellp1Phchr1PleosPC15_1Pospl1Pucgr1Schco1Serla_S7_9Sporo1Treme1Ustma1TotalAnnotation Description
Merops
2872851571382421961581491481,760
242561725201158141Water nucleophile; water bound by two Asp from monomer or dimer; all endopeptidases, from eukaryote organisms, viruses or virus-like organisms
11Water nucleophile; water bound by two Asp; all membrane-bound endopeptidases known only from eubacteria with active site on periplasmic side of cell membrane.
22111221113Water nucleophile; water bound by two Asp; all membrane-bound endopeptidases known only from eubacteria with active site on cytoplasmic side of cell membrane.
11Water nucleophile; water bound by two Asp
18151413308161418146Cysteine nucleophile; catalytic residues in the order Cys, His, Asn (or Asp) in sequence
34323624229Cysteine nucleophile; catalytic residues in the order His, Cys in sequence
2121118Cysteine nucleophile; catalytic residues in the order His, Glu (or Asp), Cys in sequence
11Cysteine nucleophile; catalytic residues in the order Glu, Cys, His in sequence
112Cysteine nucleophile; catalytic residues in the order His, Cys in sequence
45223232225Families of peptidase inhibitors not assigned to clans
112
112
432721120
2211142215Families of metallopeptidases not assigned to clans
191887911109798Water nucleophile; water bound by single zinc ion ligated to two His (within the motif HEXXH) and Glu, His or Asp
1111116Water nucleophile; water bound by single zinc ion ligated to His, Glu (within the motif HXXE) and His
11133110Water nucleophile; water bound by single zinc ion ligated to two His (within the motif HXXEH) and Glu
22111119Water nucleophile; water bound by two zinc ions ligated by Lys, Asp, Asp, Asp, Glu
99867478462Water nucleophile; water bound by two cobalt or manganese ions ligated by Asp, Asp, His, Glu, Glu
18171378399690Water nucleophile; water bound by two zinc ions ligated by His (or Asp), Asp, Glu, Asp (or Glu), His
101010278810469Water nucleophile; water bound by two zinc ions ligated by His, His or Asp, Lys or Glu, His, His.
11114Water nucleophile; water bound by single zinc ion ligated to two His (within the motif HEXXH) and Asp; membrane proteins with intramembrane active site.
66547155544Water nucleophile; water bound by single zinc ion ligated to two His and Asp (within the motif HSHP(X)9D)
22116Serine or cysteine nucleophile; catalytic residues in the order His, Asp, Ser (or Cys) in sequence; all endopeptidases
18181717178182018151Threonine, serine or cysteine nucleophile at the N-terminus of mature enzyme
1110332333139Serine or cysteine nucleophile; catalytic residues in the order Cys (or Ser), His, Glu in sequence.
1113Serine or threonine nucleophile; N-terminal nucleophile
66161021234Serine nucleophile; catalytic residues in the order Asp, His, Ser in sequence in family S8, but family S53 differs
9810140297775333150534Serine nucleophile; catalytic residues in the order Ser, Asp, His in sequence
23511315Serine nucleophile; catalytic residues in the order Ser, Lys (within the motif SXXK) in sequence
33332643128Serine nucleophile; catalytic residues in the order Ser, Lys (or His) in sequence
11111117Serine nucleophile; catalytic residues in the order Ser, His, Asp in sequence
3332142422Serine nucleophile; transmembrane protein with catalytic residues in the order Ser, His embedded in the membrane
11Families of peptidases of unknown catalytic mechanism not assigned to clans
111111118
1515101417111496111
11
22