Peptidases • Leotiomycetes
Annotations/GenomesAcema1Amore1Amyenc1Ascsa1Bissp1Blugr2BlugrR1_1Blugra1Botci1Bulin1Cadsp1Calmar1Chalo1Cocst1Elyde1Erynec1Glalo1Golci1Greab1Hymvar1Lacsu1Lepor2Leptod1Lopnit1_1Lorju1Lorma1Marbr1MelPMI1271_1Melbi2Melva1Oidma1Phimu1Phisc1Pseel1Psene1Pseudest1Rhesp1Rhier1Rutfi1Sclsc1Spafl1Themi1Thest1XylPMI703_1Zalva1TotalAnnotation Description
Merops
56225631429452514314614432426472527767231541713836915432643638967465749041241424647649565262256764831317321250341934227728717513962452117,528
34151715195561814311850162482071729213433353532102727433628412313112732161215792332990Water nucleophile; water bound by two Asp from monomer or dimer; all endopeptidases, from eukaryote organisms, viruses or virus-like organisms
111111111111113Water nucleophile; water bound by two Asp; all membrane-bound endopeptidases known only from eubacteria with active site on periplasmic side of cell membrane.
1474511341441781658252968191799108111313111817314157564321111370Water nucleophile; water bound by two Asp; all membrane-bound endopeptidases known only from eubacteria with active site on cytoplasmic side of cell membrane.
2920271929161616212537202924251825172428263934272124232835403330261419203130241818191434301,122Cysteine nucleophile; catalytic residues in the order Cys, His, Asn (or Asp) in sequence
442333342432533323432443443455434334352232245150Cysteine nucleophile; catalytic residues in the order His, Cys in sequence
2111211113123221112234253122112221231122174Cysteine nucleophile; catalytic residues in the order His, Glu (or Asp), Cys in sequence
21215131221122213121113133111412112264Cysteine nucleophile; catalytic residues in the order Glu, Cys, His in sequence
2111121110Cysteine nucleophile; catalytic residues in the order Cys, His, His in sequence
11111111111111111111111111111111111136Cysteine nucleophile; catalytic residues in the order His, Cys in sequence
722411135411846432635853246151348711752598195Water nucleophile; water bound by Gln and Glu; all endopeptidases
112Water nucleophile; water bound by Glu; all self-cleaving endopeptidases
454443335454444445543453554454545463444545354189Families of peptidase inhibitors not assigned to clans
1111116
1111217
12216
213
1222111211212221112222221212212121221159
63234417276433345445432386453523331184148
11114
7445121114210384623243511109662677857422733341157217Families of metallopeptidases not assigned to clans
169179347769933152381292171020143128171514161617221522211471322121189971120672Water nucleophile; water bound by single zinc ion ligated to two His (within the motif HEXXH) and Glu, His or Asp
1121531221112222221121111211121231111260Water nucleophile; water bound by single zinc ion ligated to His, Glu (within the motif HXXE) and His
11122222421121221211111111222211112112121112166Water nucleophile; water bound by single zinc ion ligated to two His (within the motif HXXEH) and Glu
10888115558911810811594998101099949101010101297610988565118373Water nucleophile; water bound by two cobalt or manganese ions ligated by Asp, Asp, His, Glu, Glu
3418221640554202341223823323266242624414034272618292732303741194935202317219735311,064Water nucleophile; water bound by two zinc ions ligated by His (or Asp), Asp, Glu, Asp (or Glu), His
191110121622281025923121711428172020232010119181822181926103617111188532618580Water nucleophile; water bound by two zinc ions ligated by His, His or Asp, Lys or Glu, His, His.
11114Water nucleophile; water bound by single zinc ion ligated to two His and Asp (within the motifs HXXXD and HXH)
444434444344444444444432443444444443444443344171Water nucleophile; water bound by single zinc ion ligated to two His and Asp (within the motif HSHP(X)9D)
111111111111111111119Water nucleophile; water bound by single zinc ion ligated to Asp, His and His.
23131113172411212335222354422312221286Serine or cysteine nucleophile; catalytic residues in the order His, Asp, Ser (or Cys) in sequence; all endopeptidases
2422232127161617222327272722251824202322262625242625212524282924262118202425202522222228261,048Threonine, serine or cysteine nucleophile at the N-terminus of mature enzyme
6253733365135114326226610138633751181163238444443510248Serine or cysteine nucleophile; catalytic residues in the order Cys (or Ser), His, Glu in sequence.
11Cysteine nucleophile at the N-terminus of mature enzyme; catalytic residues in the order Cys, Thr, His
422211111111121112121121112139Serine or threonine nucleophile; N-terminal nucleophile
11114Families of serine peptidases not assigned to clans
351312172344412940153518264151318162142422922261225253438303418463325141222533417906Serine nucleophile; catalytic residues in the order Asp, His, Ser in sequence in family S8, but family S53 differs
238751081102043840381318131576290106158331443511919113930028318814715769182184286274255295117526219816014410010241383042286,835Serine nucleophile; catalytic residues in the order Ser, Asp, His in sequence
18435216230521101075982726191592172219261623651313948121812476Serine nucleophile; catalytic residues in the order Ser, Lys (within the motif SXXK) in sequence
333343333333333233333334332233333244333223154134Serine nucleophile; catalytic residues in the order Ser, Lys (or His) in sequence
11Serine nucleophile; catalytic residues in the order Ser, Lys in sequence
21113222111121111122211111122131111232112112266Serine nucleophile; catalytic residues in the order Ser, His, Asp in sequence
111122211111116Serine nucleophile; catalytic residues in the order Ser, Glu, His
63323222133253413222233334446522233223331131122Serine nucleophile; transmembrane protein with catalytic residues in the order Ser, His embedded in the membrane
1211111211111122222Families of peptidases of unknown catalytic mechanism not assigned to clans
1111111111111111111111111111111111111111111144
18121715201313151213301114141412131213121413171313141126231524141512131715171217131781514675
2112111111111121111224
1124
521411461313245433344526432111248103