Peptidases • Dacrymycetes
Annotations/GenomesCalco1Calvi1Cercer1Cercru1Dacruf1Dacsp1Dactor1Dactort1Uniuni1TotalAnnotation Description
Merops
3423493923724752993354204473,431
273033294930264246312Water nucleophile; water bound by two Asp from monomer or dimer; all endopeptidases, from eukaryote organisms, viruses or virus-like organisms
22332321119Water nucleophile; water bound by two Asp; all membrane-bound endopeptidases known only from eubacteria with active site on cytoplasmic side of cell membrane.
222223333319273431244Cysteine nucleophile; catalytic residues in the order Cys, His, Asn (or Asp) in sequence
13548345538Cysteine nucleophile; catalytic residues in the order His, Cys in sequence
312224115Cysteine nucleophile; catalytic residues in the order His, Glu (or Asp), Cys in sequence
111115Cysteine nucleophile; catalytic residues in the order Glu, Cys, His in sequence
32332242122Water nucleophile; water bound by Gln and Glu; all endopeptidases
33333333327Families of peptidase inhibitors not assigned to clans
11
22232122319
22243225325Families of metallopeptidases not assigned to clans
991191058111486Water nucleophile; water bound by single zinc ion ligated to two His (within the motif HEXXH) and Glu, His or Asp
12112119Water nucleophile; water bound by single zinc ion ligated to two His (within the motif HXXEH) and Glu
111121119Water nucleophile; water bound by two zinc ions ligated by Lys, Asp, Asp, Asp, Glu
9912109101011989Water nucleophile; water bound by two cobalt or manganese ions ligated by Asp, Asp, His, Glu, Glu
232523182718162131202Water nucleophile; water bound by two zinc ions ligated by His (or Asp), Asp, Glu, Asp (or Glu), His
1099132112131619122Water nucleophile; water bound by two zinc ions ligated by His, His or Asp, Lys or Glu, His, His.
1111111119Water nucleophile; water bound by single zinc ion ligated to two His (within the motif HEXXH) and Asp; membrane proteins with intramembrane active site.
46555555545Water nucleophile; water bound by single zinc ion ligated to two His and Asp (within the motif HSHP(X)9D)
11114Asparagine nucleophile; catalytic residues in the order Asp, Asn in sequence; all self-processing endopeptidases
1112117Serine or cysteine nucleophile; catalytic residues in the order His, Asp, Ser (or Cys) in sequence; all endopeptidases
222123242323242324207Threonine, serine or cysteine nucleophile at the N-terminus of mature enzyme
33335334330Serine or cysteine nucleophile; catalytic residues in the order Cys (or Ser), His, Glu in sequence.
13116Serine or threonine nucleophile; N-terminal nucleophile
12129111710111414110Serine nucleophile; catalytic residues in the order Asp, His, Ser in sequence in family S8, but family S53 differs
1281361611562041021301631831,363Serine nucleophile; catalytic residues in the order Ser, Asp, His in sequence
151325131512131817141Serine nucleophile; catalytic residues in the order Ser, Lys (within the motif SXXK) in sequence
52234546435Serine nucleophile; catalytic residues in the order Ser, Lys (or His) in sequence
11111121211Serine nucleophile; catalytic residues in the order Ser, His, Asp in sequence
112Serine nucleophile; catalytic residues in the order His, Ser within the motif HXS.
112Serine nucleophile; catalytic residues in the order Ser, Glu, His
43342333631Serine nucleophile; transmembrane protein with catalytic residues in the order Ser, His embedded in the membrane
11Families of peptidases of unknown catalytic mechanism not assigned to clans
1111111119
211914111714131514138
11
11
112
36651143332