Peptidases • Kluyveromyces lactis
Annotations/GenomesAscru1Babin1Canar1Canca1Canta1Cante1Cybja1Dekbr2Hanpo2Hanva1_1Hypbu1Klula1Lipst1_1Metbi1Nadfu1Pacta1_2Picme2Picst3Sacce1Spapa3Wican1TotalAnnotation Description
Merops
1551711411481491511671431511111531272001421591521341481371571823,178
1012124151014656105101261061281812203Water nucleophile; water bound by two Asp from monomer or dimer; all endopeptidases, from eukaryote organisms, viruses or virus-like organisms
213Water nucleophile; water bound by two Asp; all membrane-bound endopeptidases known only from eubacteria with active site on periplasmic side of cell membrane.
1112111111111115Water nucleophile; water bound by two Asp; all membrane-bound endopeptidases known only from eubacteria with active site on cytoplasmic side of cell membrane.
141712161313161514111513221416131312151418306Cysteine nucleophile; catalytic residues in the order Cys, His, Asn (or Asp) in sequence
94212223334222322323460Cysteine nucleophile; catalytic residues in the order His, Cys in sequence
1211112121114Cysteine nucleophile; catalytic residues in the order His, Glu (or Asp), Cys in sequence
11Cysteine nucleophile; catalytic residues in the order Cys, His, His in sequence
1111111119Cysteine nucleophile; catalytic residues in the order His, Cys in sequence
1214Water nucleophile; water bound by Gln and Glu; all endopeptidases
44324443423234542424471Families of peptidase inhibitors not assigned to clans
112
11
111115
11111122111121118
22222232232232222232448
11111211111211111120Families of metallopeptidases not assigned to clans
913896666661171067769796160Water nucleophile; water bound by single zinc ion ligated to two His (within the motif HEXXH) and Glu, His or Asp
1111111111111111111120Water nucleophile; water bound by single zinc ion ligated to His, Glu (within the motif HXXE) and His
1222111123112151111131Water nucleophile; water bound by single zinc ion ligated to two His (within the motif HXXEH) and Glu
11Water nucleophile; water bound by two zinc ions ligated by Lys, Asp, Asp, Asp, Glu
676877778664777685576137Water nucleophile; water bound by two cobalt or manganese ions ligated by Asp, Asp, His, Glu, Glu
8141013121419141311121310111514111091019262Water nucleophile; water bound by two zinc ions ligated by His (or Asp), Asp, Glu, Asp (or Glu), His
546337799245544973436109Water nucleophile; water bound by two zinc ions ligated by His, His or Asp, Lys or Glu, His, His.
3244445433143445323368Water nucleophile; water bound by single zinc ion ligated to two His and Asp (within the motif HSHP(X)9D)
1113Serine or cysteine nucleophile; catalytic residues in the order His, Asp, Ser (or Cys) in sequence; all endopeptidases
191616201818181818161820191620181917201719380Threonine, serine or cysteine nucleophile at the N-terminus of mature enzyme
232333132142323282352Serine or cysteine nucleophile; catalytic residues in the order Cys (or Ser), His, Glu in sequence.
1111111111111111117Serine or threonine nucleophile; N-terminal nucleophile
733633533442634433310486Serine nucleophile; catalytic residues in the order Asp, His, Ser in sequence in family S8, but family S53 differs
314530293334322733213526602924292435252844674Serine nucleophile; catalytic residues in the order Ser, Asp, His in sequence
111311121112117Serine nucleophile; catalytic residues in the order Ser, Lys (within the motif SXXK) in sequence
43333333333333433233364Serine nucleophile; catalytic residues in the order Ser, Lys (or His) in sequence
11125Serine nucleophile; catalytic residues in the order Ser, His, Asp in sequence
111115Serine nucleophile; catalytic residues in the order His, Ser within the motif HXS.
11Serine nucleophile; catalytic residues in the order Ser, Glu, His
33321234212352542223458Serine nucleophile; transmembrane protein with catalytic residues in the order Ser, His embedded in the membrane
2215Families of peptidases of unknown catalytic mechanism not assigned to clans
1111111111111111111120
8761099911979813111498891010194
1113
112111326220
22
11114