Peptidases • Debaryomycetaceae
Annotations/GenomesBabin1Canalb1Canta1Cante1Debha1Hypbu1Lodelo1Meygui1Petxy1Picst3Schcoi1Schsti1Spaarb1Spapa3TotalAnnotation Description
Merops
1711501491511511531281701631481451531561572,145
12191510610111681210131918179Water nucleophile; water bound by two Asp from monomer or dimer; all endopeptidases, from eukaryote organisms, viruses or virus-like organisms
1111111111111Water nucleophile; water bound by two Asp; all membrane-bound endopeptidases known only from eubacteria with active site on cytoplasmic side of cell membrane.
1715131313151016131211121814192Cysteine nucleophile; catalytic residues in the order Cys, His, Asn (or Asp) in sequence
4222242233233337Cysteine nucleophile; catalytic residues in the order His, Cys in sequence
2114Cysteine nucleophile; catalytic residues in the order His, Glu (or Asp), Cys in sequence
1111111111111Cysteine nucleophile; catalytic residues in the order His, Cys in sequence
11Water nucleophile; water bound by Gln and Glu; all endopeptidases
4444333434444452Families of peptidase inhibitors not assigned to clans
11
11111121111113
2222222122222227
111211111111114Families of metallopeptidases not assigned to clans
1356651168695779103Water nucleophile; water bound by single zinc ion ligated to two His (within the motif HEXXH) and Glu, His or Asp
1111111111111114Water nucleophile; water bound by single zinc ion ligated to His, Glu (within the motif HXXE) and His
2111111121111116Water nucleophile; water bound by single zinc ion ligated to two His (within the motif HXXEH) and Glu
11Water nucleophile; water bound by two zinc ions ligated by Lys, Asp, Asp, Asp, Glu
7777765865657790Water nucleophile; water bound by two cobalt or manganese ions ligated by Asp, Asp, His, Glu, Glu
141012141412101420101310910172Water nucleophile; water bound by two zinc ions ligated by His (or Asp), Asp, Glu, Asp (or Glu), His
4337442893433360Water nucleophile; water bound by two zinc ions ligated by His, His or Asp, Lys or Glu, His, His.
2244332333233340Water nucleophile; water bound by single zinc ion ligated to two His and Asp (within the motif HSHP(X)9D)
11Water nucleophile; water bound by single zinc ion ligated to Asp, His and His.
11Asparagine nucleophile; catalytic residues in the order Asp, Asn in sequence; all self-processing endopeptidases
1619181818181919191718171817251Threonine, serine or cysteine nucleophile at the N-terminus of mature enzyme
2333625232121237Serine or cysteine nucleophile; catalytic residues in the order Cys (or Ser), His, Glu in sequence.
1111111111111114Serine or threonine nucleophile; N-terminal nucleophile
34333433436351057Serine nucleophile; catalytic residues in the order Asp, His, Ser in sequence in family S8, but family S53 differs
4532333436352439363532393128479Serine nucleophile; catalytic residues in the order Ser, Asp, His in sequence
1111421112121120Serine nucleophile; catalytic residues in the order Ser, Lys (within the motif SXXK) in sequence
3233333332333340Serine nucleophile; catalytic residues in the order Ser, Lys (or His) in sequence
11Serine nucleophile; catalytic residues in the order His, Ser within the motif HXS.
3212322232323333Serine nucleophile; transmembrane protein with catalytic residues in the order Ser, His embedded in the membrane
1111111111111114
7899109910881081010125
112
1221111216461231
11