Peptidases • Cadophora sp. DSE1049 v1.0
Annotations/GenomesAmore1Botci1Cadsp1Melbi2Oidma1Perma1Sclsc1TotalAnnotation Description
Merops
2563247254956225282773,227
15183127361712156Water nucleophile; water bound by two Asp from monomer or dimer; all endopeptidases, from eukaryote organisms, viruses or virus-like organisms
112Water nucleophile; water bound by two Asp; all membrane-bound endopeptidases known only from eubacteria with active site on periplasmic side of cell membrane.
7417131111669Water nucleophile; water bound by two Asp; all membrane-bound endopeptidases known only from eubacteria with active site on cytoplasmic side of cell membrane.
20213735333318197Cysteine nucleophile; catalytic residues in the order Cys, His, Asn (or Asp) in sequence
423544224Cysteine nucleophile; catalytic residues in the order His, Cys in sequence
11121118Cysteine nucleophile; catalytic residues in the order His, Glu (or Asp), Cys in sequence
15113112Cysteine nucleophile; catalytic residues in the order Glu, Cys, His in sequence
112Cysteine nucleophile; catalytic residues in the order Cys, His, His in sequence
1111116Cysteine nucleophile; catalytic residues in the order His, Cys in sequence
2346133233Water nucleophile; water bound by Gln and Glu; all endopeptidases
11Water nucleophile; water bound by Glu; all self-cleaving endopeptidases
555555535Families of peptidase inhibitors not assigned to clans
112
123
22
22
22111119
3473611337
11
4410788344Families of metallopeptidases not assigned to clans
99331715218112Water nucleophile; water bound by single zinc ion ligated to two His (within the motif HEXXH) and Glu, His or Asp
132118319Water nucleophile; water bound by single zinc ion ligated to His, Glu (within the motif HXXE) and His
141211212Water nucleophile; water bound by single zinc ion ligated to two His (within the motif HXXEH) and Glu
881110109864Water nucleophile; water bound by two cobalt or manganese ions ligated by Asp, Asp, His, Glu, Glu
18204127303217185Water nucleophile; water bound by two zinc ions ligated by His (or Asp), Asp, Glu, Asp (or Glu), His
118251818168104Water nucleophile; water bound by two zinc ions ligated by His, His or Asp, Lys or Glu, His, His.
444443427Water nucleophile; water bound by single zinc ion ligated to two His and Asp (within the motif HSHP(X)9D)
1113Water nucleophile; water bound by single zinc ion ligated to Asp, His and His.
37425223Serine or cysteine nucleophile; catalytic residues in the order His, Asp, Ser (or Cys) in sequence; all endopeptidases
22222724292225171Threonine, serine or cysteine nucleophile at the N-terminus of mature enzyme
26135817455Serine or cysteine nucleophile; catalytic residues in the order Cys (or Ser), His, Glu in sequence.
22221110Serine or threonine nucleophile; N-terminal nucleophile
11Families of serine peptidases not assigned to clans
13124025381512155Serine nucleophile; catalytic residues in the order Asp, His, Ser in sequence in family S8, but family S53 differs
751313151842742381001,317Serine nucleophile; catalytic residues in the order Ser, Asp, His in sequence
46302226144106Serine nucleophile; catalytic residues in the order Ser, Lys (within the motif SXXK) in sequence
333334221Serine nucleophile; catalytic residues in the order Ser, Lys (or His) in sequence
11Serine nucleophile; catalytic residues in the order Ser, Lys in sequence
111231110Serine nucleophile; catalytic residues in the order Ser, His, Asp in sequence
11Serine nucleophile; catalytic residues in the order Ser, Glu, His
313623321Serine nucleophile; transmembrane protein with catalytic residues in the order Ser, His embedded in the membrane
123Families of peptidases of unknown catalytic mechanism not assigned to clans
1111116
12123023241417132
213
21445420