Peptidases • Naohidea sebacea CBS 8477 (P95) v1.0
Annotations/GenomesAgahy1Chiap1Croqu1Eryha1Hetpy1Hyabl1Melli1Mellp1Mixos1Naose1Pucgr1Pucst1Rhoba1_1Rhomi1Rhosp1Sporo1Trisp1TotalAnnotation Description
Merops
1781971922321721811781832102241851871651581742,816
1119271312123930231410149117251Water nucleophile; water bound by two Asp from monomer or dimer; all endopeptidases, from eukaryote organisms, viruses or virus-like organisms
11Water nucleophile; water bound by two Asp; all membrane-bound endopeptidases known only from eubacteria with active site on periplasmic side of cell membrane.
21151111122322126Water nucleophile; water bound by two Asp; all membrane-bound endopeptidases known only from eubacteria with active site on cytoplasmic side of cell membrane.
201819182221141120222013151617266Cysteine nucleophile; catalytic residues in the order Cys, His, Asn (or Asp) in sequence
33223332232322237Cysteine nucleophile; catalytic residues in the order His, Cys in sequence
142121112Cysteine nucleophile; catalytic residues in the order His, Glu (or Asp), Cys in sequence
1111112111112Cysteine nucleophile; catalytic residues in the order Glu, Cys, His in sequence
11114Cysteine nucleophile; catalytic residues in the order His, Cys in sequence
33322222423223338Families of peptidase inhibitors not assigned to clans
111115
112
111115
23232231133121130
111111111111113Families of metallopeptidases not assigned to clans
1095668107101110971016134Water nucleophile; water bound by single zinc ion ligated to two His (within the motif HEXXH) and Glu, His or Asp
2111111121214Water nucleophile; water bound by single zinc ion ligated to His, Glu (within the motif HXXE) and His
11136Water nucleophile; water bound by single zinc ion ligated to two His (within the motif HXXEH) and Glu
1111111212111116Water nucleophile; water bound by two zinc ions ligated by Lys, Asp, Asp, Asp, Glu
66667744777677592Water nucleophile; water bound by two cobalt or manganese ions ligated by Asp, Asp, His, Glu, Glu
810714884610141113995136Water nucleophile; water bound by two zinc ions ligated by His (or Asp), Asp, Glu, Asp (or Glu), His
565116655791081085106Water nucleophile; water bound by two zinc ions ligated by His, His or Asp, Lys or Glu, His, His.
11111111111112Water nucleophile; water bound by single zinc ion ligated to two His (within the motif HEXXH) and Asp; membrane proteins with intramembrane active site.
65564674557555580Water nucleophile; water bound by single zinc ion ligated to two His and Asp (within the motif HSHP(X)9D)
111115Asparagine nucleophile; catalytic residues in the order Asp, Asn in sequence; all self-processing endopeptidases
11114Serine or cysteine nucleophile; catalytic residues in the order His, Asp, Ser (or Cys) in sequence; all endopeptidases
191723191819171718261820171817283Threonine, serine or cysteine nucleophile at the N-terminus of mature enzyme
32122213122223129Serine or cysteine nucleophile; catalytic residues in the order Cys (or Ser), His, Glu in sequence.
11114Serine or threonine nucleophile; N-terminal nucleophile
2473335841612121374Serine nucleophile; catalytic residues in the order Asp, His, Ser in sequence in family S8, but family S53 differs
465354864449436067524756423343775Serine nucleophile; catalytic residues in the order Ser, Asp, His in sequence
2162213241529Serine nucleophile; catalytic residues in the order Ser, Lys (within the motif SXXK) in sequence
33343332325334448Serine nucleophile; catalytic residues in the order Ser, Lys (or His) in sequence
11Serine nucleophile; catalytic residues in the order Ser, Lys in sequence
21112112121217Serine nucleophile; catalytic residues in the order Ser, His, Asp in sequence
11Serine nucleophile; catalytic residues in the order His, Ser within the motif HXS.
34242214114432239Serine nucleophile; transmembrane protein with catalytic residues in the order Ser, His embedded in the membrane
111111111111113
1214111213129915181112141411187
213
11
1135