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Peptidases • Schizophyllum commune H4-8 v3.0
Annotations/GenomesAgabi_varbisH97_2Copci1Fishe1Phchr2PleosPC15_2Schco1Schco2Schco3Schco_LoeD_1Schco_TatD_1TotalAnnotation Description
Merops
2872872743543473453363422,572
2411306224292730237Water nucleophile; water bound by two Asp from monomer or dimer; all endopeptidases, from eukaryote organisms, viruses or virus-like organisms
11Water nucleophile; water bound by two Asp; all membrane-bound endopeptidases known only from eubacteria with active site on periplasmic side of cell membrane.
222123214Water nucleophile; water bound by two Asp; all membrane-bound endopeptidases known only from eubacteria with active site on cytoplasmic side of cell membrane.
55Water nucleophile; water bound by two Asp
1815171618201819141Cysteine nucleophile; catalytic residues in the order Cys, His, Asn (or Asp) in sequence
3563956542Cysteine nucleophile; catalytic residues in the order His, Cys in sequence
2132322116Cysteine nucleophile; catalytic residues in the order His, Glu (or Asp), Cys in sequence
11Cysteine nucleophile; catalytic residues in the order Glu, Cys, His in sequence
41111118Water nucleophile; water bound by Gln and Glu; all endopeptidases
4725222226Families of peptidase inhibitors not assigned to clans
112
11
111222211
4524677641
2323333322Families of metallopeptidases not assigned to clans
193012932222322169Water nucleophile; water bound by single zinc ion ligated to two His (within the motif HEXXH) and Glu, His or Asp
11212119Water nucleophile; water bound by single zinc ion ligated to His, Glu (within the motif HXXE) and His
111111118Water nucleophile; water bound by single zinc ion ligated to two His (within the motif HXXEH) and Glu
2111121110Water nucleophile; water bound by two zinc ions ligated by Lys, Asp, Asp, Asp, Glu
9710991091174Water nucleophile; water bound by two cobalt or manganese ions ligated by Asp, Asp, His, Glu, Glu
1822181517232122156Water nucleophile; water bound by two zinc ions ligated by His (or Asp), Asp, Glu, Asp (or Glu), His
10812101012121185Water nucleophile; water bound by two zinc ions ligated by His, His or Asp, Lys or Glu, His, His.
1113Water nucleophile; water bound by single zinc ion ligated to two His (within the motif HEXXH) and Asp; membrane proteins with intramembrane active site.
11Water nucleophile; water bound by single zinc ion ligated to two His and Asp (within the motifs HXXXD and HXH)
6766655647Water nucleophile; water bound by single zinc ion ligated to two His and Asp (within the motif HSHP(X)9D)
11Asparagine nucleophile; catalytic residues in the order Asp, Asn in sequence; all self-processing endopeptidases
11Asparagine nucleophile; all self-processing endopeptidases
213Serine or cysteine nucleophile; catalytic residues in the order His, Asp, Ser (or Cys) in sequence; all endopeptidases
1819242220222123169Threonine, serine or cysteine nucleophile at the N-terminus of mature enzyme
11856876960Serine or cysteine nucleophile; catalytic residues in the order Cys (or Ser), His, Glu in sequence.
11114Serine or threonine nucleophile; N-terminal nucleophile
686121266662Serine nucleophile; catalytic residues in the order Asp, His, Ser in sequence in family S8, but family S53 differs
989982127127132131132928Serine nucleophile; catalytic residues in the order Ser, Asp, His in sequence
2213334422Serine nucleophile; catalytic residues in the order Ser, Lys (within the motif SXXK) in sequence
3232333322Serine nucleophile; catalytic residues in the order Ser, Lys (or His) in sequence
112111119Serine nucleophile; catalytic residues in the order Ser, His, Asp in sequence
3344444329Serine nucleophile; transmembrane protein with catalytic residues in the order Ser, His embedded in the membrane
111111118
1510131423121412113
11