Peptidases • Mycena
Annotations/GenomesMyc59_1Mycalb1Mycale1Mycami1Mycbel1Myccro1Mycepi1Mycfil1Mycflo1Mycgal1Mycgale1Mychae1Myclat1Myclep1Mycmac1Mycmet1Mycoli1Mycpol1Mycpur1Mycreb1Mycros1Mycrub1Mycsan1Mycvit1Mycvul1TotalAnnotation Description
Merops
6729226795904316608957426031,0519904758611,3125908341,6688835791,1208239268106671,03620,819
568868754568917739115884991136578317184568979886975762,013Water nucleophile; water bound by two Asp from monomer or dimer; all endopeptidases, from eukaryote organisms, viruses or virus-like organisms
22Water nucleophile; water bound by two Asp; all membrane-bound endopeptidases known only from eubacteria with active site on periplasmic side of cell membrane.
2422119121022673544543315896Water nucleophile; water bound by two Asp; all membrane-bound endopeptidases known only from eubacteria with active site on cytoplasmic side of cell membrane.
22Water nucleophile; water bound by two Asp
4238293022344943334658284086315011444286551414033991,174Cysteine nucleophile; catalytic residues in the order Cys, His, Asn (or Asp) in sequence
16119589361652111714342012241361413178917355Cysteine nucleophile; catalytic residues in the order His, Cys in sequence
342416223241110627422323682Cysteine nucleophile; catalytic residues in the order His, Glu (or Asp), Cys in sequence
11Cysteine nucleophile; catalytic residues in the order Glu, Cys, His in sequence
112Cysteine nucleophile: catalytic residues in the order Cys, His in sequence
1113Cysteine nucleophile; catalytic residues in the order Cys, His, His in sequence
4544158628124697116210891314412174Water nucleophile; water bound by Gln and Glu; all endopeptidases
34543333333339311444363334100Families of peptidase inhibitors not assigned to clans
112
2114
11112111111111116
314
211131112111111120
41049474656751210652083465776170
211362556141372583515962345126159Families of metallopeptidases not assigned to clans
28392019274525333334161934531421543517655034182658817Water nucleophile; water bound by single zinc ion ligated to two His (within the motif HEXXH) and Glu, His or Asp
22222113711111121211237Water nucleophile; water bound by single zinc ion ligated to His, Glu (within the motif HXXE) and His
11211111321111141111111131Water nucleophile; water bound by single zinc ion ligated to two His (within the motif HXXEH) and Glu
211211111121211121111111130Water nucleophile; water bound by two zinc ions ligated by Lys, Asp, Asp, Asp, Glu
121213121191011131414119261112171411181312111317326Water nucleophile; water bound by two cobalt or manganese ions ligated by Asp, Asp, His, Glu, Glu
36383324193126241950391844452541522724603435261935824Water nucleophile; water bound by two zinc ions ligated by His (or Asp), Asp, Glu, Asp (or Glu), His
25221518131825191529251742402218372517262223222628589Water nucleophile; water bound by two zinc ions ligated by His, His or Asp, Lys or Glu, His, His.
111111112111111111111111126Water nucleophile; water bound by single zinc ion ligated to two His (within the motif HEXXH) and Asp; membrane proteins with intramembrane active site.
311311221117241661255Water nucleophile; water bound by single zinc ion ligated to two His and Asp (within the motifs HXXXD and HXH)
9767661176191366169710769795637237Water nucleophile; water bound by single zinc ion ligated to two His and Asp (within the motif HSHP(X)9D)
111111111110Water nucleophile; water bound by single zinc ion ligated to Asp, His and His.
22111211112Asparagine nucleophile; catalytic residues in the order Asp, Asn in sequence; all self-processing endopeptidases
11Asparagine nucleophile; all self-processing endopeptidases
2111122222112441132439Serine or cysteine nucleophile; catalytic residues in the order His, Asp, Ser (or Cys) in sequence; all endopeptidases
28283526213531414351372431502343404342463629343442893Threonine, serine or cysteine nucleophile at the N-terminus of mature enzyme
712910161217112512751098112313698141076277Serine or cysteine nucleophile; catalytic residues in the order Cys (or Ser), His, Glu in sequence.
323326121131321123221512255Serine or threonine nucleophile; N-terminal nucleophile
11Families of serine peptidases not assigned to clans
42876231284070572110511333741184487172574610863799842821,759Serine nucleophile; catalytic residues in the order Asp, His, Ser in sequence in family S8, but family S53 differs
2734283012401652603913072784144261943705402413487494152444733404113672844278,886Serine nucleophile; catalytic residues in the order Ser, Asp, His in sequence
2029262092125281039341118501732502711542935241931669Serine nucleophile; catalytic residues in the order Ser, Lys (within the motif SXXK) in sequence
65434457457464431153654564124Serine nucleophile; catalytic residues in the order Ser, Lys (or His) in sequence
11Serine nucleophile; catalytic residues in the order Ser, Lys in sequence
111311331111111131111111133Serine nucleophile; catalytic residues in the order Ser, His, Asp in sequence
11114Serine nucleophile; catalytic residues in the order Ser, Glu, His
56543544448448447641155344125Serine nucleophile; transmembrane protein with catalytic residues in the order Ser, His embedded in the membrane
21111211212Families of peptidases of unknown catalytic mechanism not assigned to clans
111111111121111111111111126
31151016131728151418321617301712451916192332171319504
1111116
1113
112115121241221128