Peptidases • Globomyces pollinis-pini Arg68 v1.0
Annotations/GenomesBatde5Catan2Caupr1Ganpr1Glopol1Pirfi3Rhihy1Spipu1TotalAnnotation Description
Merops
3142501523413722283602102,227
103176271278180Water nucleophile; water bound by two Asp from monomer or dimer; all endopeptidases, from eukaryote organisms, viruses or virus-like organisms
11Water nucleophile; water bound by two Asp; all membrane-bound endopeptidases known only from eubacteria with active site on periplasmic side of cell membrane.
222223215Water nucleophile; water bound by two Asp; all membrane-bound endopeptidases known only from eubacteria with active site on cytoplasmic side of cell membrane.
1915152117202215144Cysteine nucleophile; catalytic residues in the order Cys, His, Asn (or Asp) in sequence
39275146349Cysteine nucleophile; catalytic residues in the order His, Cys in sequence
2112214215Cysteine nucleophile; catalytic residues in the order His, Glu (or Asp), Cys in sequence
11111117Cysteine nucleophile; catalytic residues in the order Glu, Cys, His in sequence
112Cysteine nucleophile; catalytic residues in the order His, Cys in sequence
112Cysteine nucleophile; catalytic residues in the order His, Cys in sequence
11Water nucleophile; water bound by Glu; all self-cleaving endopeptidases
511257511450Families of peptidase inhibitors not assigned to clans
22
11
11
11111128
11125
112
111414113Families of metallopeptidases not assigned to clans
3517151849302511200Water nucleophile; water bound by single zinc ion ligated to two His (within the motif HEXXH) and Glu, His or Asp
1116326231Water nucleophile; water bound by single zinc ion ligated to His, Glu (within the motif HXXE) and His
22111119Water nucleophile; water bound by single zinc ion ligated to two His (within the motif HXXEH) and Glu
2524335428Water nucleophile; water bound by two zinc ions ligated by Lys, Asp, Asp, Asp, Glu
78477511958Water nucleophile; water bound by two cobalt or manganese ions ligated by Asp, Asp, His, Glu, Glu
1199161852512105Water nucleophile; water bound by two zinc ions ligated by His (or Asp), Asp, Glu, Asp (or Glu), His
44213519543Water nucleophile; water bound by two zinc ions ligated by His, His or Asp, Lys or Glu, His, His.
1111116Water nucleophile; water bound by single zinc ion ligated to two His (within the motif HEXXH) and Asp; membrane proteins with intramembrane active site.
11Water nucleophile; water bound by two zinc ions ligated by Asp, Glu, His, His, Glu
6743755441Water nucleophile; water bound by single zinc ion ligated to two His and Asp (within the motif HSHP(X)9D)
111126Asparagine nucleophile; catalytic residues in the order Asp, Asn in sequence; all self-processing endopeptidases
11Asparagine nucleophile; catalytic residues in the order Asn, Glu in sequence; all self-processing endopeptidases
9113281355Serine or cysteine nucleophile; catalytic residues in the order His, Asp, Ser (or Cys) in sequence; all endopeptidases
1519182119171919147Threonine, serine or cysteine nucleophile at the N-terminus of mature enzyme
5335439537Serine or cysteine nucleophile; catalytic residues in the order Cys (or Ser), His, Glu in sequence.
141219Serine or threonine nucleophile; N-terminal nucleophile
2512451781099Serine nucleophile; catalytic residues in the order Asp, His, Ser in sequence in family S8, but family S53 differs
44362511988589849517Serine nucleophile; catalytic residues in the order Ser, Asp, His in sequence
15162613162Serine nucleophile; catalytic residues in the order Ser, Lys (within the motif SXXK) in sequence
5745535741Serine nucleophile; catalytic residues in the order Ser, Lys (or His) in sequence
11Serine nucleophile; catalytic residues in the order Ser, Lys in sequence
1113312214Serine nucleophile; catalytic residues in the order Ser, His, Asp in sequence
11Serine nucleophile; catalytic residues in the order Ser, Glu, His
3626555436Serine nucleophile; transmembrane protein with catalytic residues in the order Ser, His embedded in the membrane
22Families of peptidases of unknown catalytic mechanism not assigned to clans
11112118
2412221724153115160
262111