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Peptidases • Podospora appendiculata CBS 314.62 v1.0
Annotations/GenomesApope1Bombom1Cersc1Podan3Podans1Podap1Podcur1Poddi1TotalAnnotation Description
Merops
4023173102952933153583922,682
2722222121242631194Water nucleophile; water bound by two Asp from monomer or dimer; all endopeptidases, from eukaryote organisms, viruses or virus-like organisms
11114Water nucleophile; water bound by two Asp; all membrane-bound endopeptidases known only from eubacteria with active site on periplasmic side of cell membrane.
6232232323Water nucleophile; water bound by two Asp; all membrane-bound endopeptidases known only from eubacteria with active site on cytoplasmic side of cell membrane.
2018201817191618146Cysteine nucleophile; catalytic residues in the order Cys, His, Asn (or Asp) in sequence
3433334427Cysteine nucleophile; catalytic residues in the order His, Cys in sequence
1111116Cysteine nucleophile; catalytic residues in the order His, Glu (or Asp), Cys in sequence
111111118Cysteine nucleophile; catalytic residues in the order Glu, Cys, His in sequence
1113Cysteine nucleophile; catalytic residues in the order His, Cys in sequence
213Cysteine nucleophile; catalytic residues in the order Cys, His, His in sequence
111111118Cysteine nucleophile; catalytic residues in the order His, Cys in sequence
6444445536Water nucleophile; water bound by Gln and Glu; all endopeptidases
111115Water nucleophile; water bound by Glu; all self-cleaving endopeptidases
3553343531Families of peptidase inhibitors not assigned to clans
11
2122222215
5434454534
4624412326Families of metallopeptidases not assigned to clans
1812161411152216124Water nucleophile; water bound by single zinc ion ligated to two His (within the motif HEXXH) and Glu, His or Asp
4454443432Water nucleophile; water bound by single zinc ion ligated to His, Glu (within the motif HXXE) and His
2212222215Water nucleophile; water bound by single zinc ion ligated to two His (within the motif HXXEH) and Glu
9777777859Water nucleophile; water bound by two cobalt or manganese ions ligated by Asp, Asp, His, Glu, Glu
2320221918221925168Water nucleophile; water bound by two zinc ions ligated by His (or Asp), Asp, Glu, Asp (or Glu), His
1212111012141416101Water nucleophile; water bound by two zinc ions ligated by His, His or Asp, Lys or Glu, His, His.
3324333425Water nucleophile; water bound by single zinc ion ligated to two His and Asp (within the motif HSHP(X)9D)
11Water nucleophile; water bound by single zinc ion ligated to Asp, His and His.
111111410Serine or cysteine nucleophile; catalytic residues in the order His, Asp, Ser (or Cys) in sequence; all endopeptidases
2323222221242322180Threonine, serine or cysteine nucleophile at the N-terminus of mature enzyme
8653456845Serine or cysteine nucleophile; catalytic residues in the order Cys (or Ser), His, Glu in sequence.
112Serine or threonine nucleophile; N-terminal nucleophile
2316171614171920142Serine nucleophile; catalytic residues in the order Asp, His, Ser in sequence in family S8, but family S53 differs
154106105104106105139142961Serine nucleophile; catalytic residues in the order Ser, Asp, His in sequence
1411666581268Serine nucleophile; catalytic residues in the order Ser, Lys (within the motif SXXK) in sequence
3333433325Serine nucleophile; catalytic residues in the order Ser, Lys (or His) in sequence
111111118Serine nucleophile; catalytic residues in the order Ser, His, Asp in sequence
1113Serine nucleophile; catalytic residues in the order Ser, Glu, His
3333222321Serine nucleophile; transmembrane protein with catalytic residues in the order Ser, His embedded in the membrane
1113Families of peptidases of unknown catalytic mechanism not assigned to clans
111111118
111012101212131393
1113
32223315