Peptidases • Entomophthoromycotina
Annotations/GenomesBasme2finSCConco1Conth1Zoorad1TotalAnnotation Description
Merops
5364393504901,815
1822426Water nucleophile; water bound by two Asp from monomer or dimer; all endopeptidases, from eukaryote organisms, viruses or virus-like organisms
123Water nucleophile; water bound by two Asp; all membrane-bound endopeptidases known only from eubacteria with active site on periplasmic side of cell membrane.
31116Water nucleophile; water bound by two Asp; all membrane-bound endopeptidases known only from eubacteria with active site on cytoplasmic side of cell membrane.
3322171688Cysteine nucleophile; catalytic residues in the order Cys, His, Asn (or Asp) in sequence
656522Cysteine nucleophile; catalytic residues in the order His, Cys in sequence
711211Cysteine nucleophile; catalytic residues in the order His, Glu (or Asp), Cys in sequence
1135Cysteine nucleophile; catalytic residues in the order Glu, Cys, His in sequence
2125Water nucleophile; water bound by Glu; all self-cleaving endopeptidases
1576533Families of peptidase inhibitors not assigned to clans
11
123
516
33
11
22
33
11
31217
2114
21115Families of metallopeptidases not assigned to clans
53291848148Water nucleophile; water bound by single zinc ion ligated to two His (within the motif HEXXH) and Glu, His or Asp
73011654Water nucleophile; water bound by single zinc ion ligated to His, Glu (within the motif HXXE) and His
811717Water nucleophile; water bound by single zinc ion ligated to two His (within the motif HXXEH) and Glu
523414Water nucleophile; water bound by two zinc ions ligated by Lys, Asp, Asp, Asp, Glu
1187632Water nucleophile; water bound by two cobalt or manganese ions ligated by Asp, Asp, His, Glu, Glu
33402512110Water nucleophile; water bound by two zinc ions ligated by His (or Asp), Asp, Glu, Asp (or Glu), His
3059448Water nucleophile; water bound by two zinc ions ligated by His, His or Asp, Lys or Glu, His, His.
11114Water nucleophile; water bound by single zinc ion ligated to two His (within the motif HEXXH) and Asp; membrane proteins with intramembrane active site.
445316Water nucleophile; water bound by single zinc ion ligated to two His and Asp (within the motif HSHP(X)9D)
11Asparagine nucleophile; catalytic residues in the order Asp, Asn in sequence; all self-processing endopeptidases
227555182334Serine or cysteine nucleophile; catalytic residues in the order His, Asp, Ser (or Cys) in sequence; all endopeptidases
3624192099Threonine, serine or cysteine nucleophile at the N-terminus of mature enzyme
102131237Serine or cysteine nucleophile; catalytic residues in the order Cys (or Ser), His, Glu in sequence.
1124Serine or threonine nucleophile; N-terminal nucleophile
73462934182Serine nucleophile; catalytic residues in the order Asp, His, Ser in sequence in family S8, but family S53 differs
91906970320Serine nucleophile; catalytic residues in the order Ser, Asp, His in sequence
234817Serine nucleophile; catalytic residues in the order Ser, Lys (within the motif SXXK) in sequence
6106729Serine nucleophile; catalytic residues in the order Ser, Lys (or His) in sequence
12115Serine nucleophile; catalytic residues in the order Ser, His, Asp in sequence
556622Serine nucleophile; transmembrane protein with catalytic residues in the order Ser, His embedded in the membrane
11Families of peptidases of unknown catalytic mechanism not assigned to clans
21115
2817201277
1113
11