Peptidases • Rhodotorula glutinis v1.0
Annotations/GenomesHetpy1Hyabl1Leucr1Mereb1Micvi1Rhoba1_1Rhoglu1Rhoto1Spopa1Sporo1TotalAnnotation Description
Merops
1721812302911901851801831801581,950
1212143016109111511140Water nucleophile; water bound by two Asp from monomer or dimer; all endopeptidases, from eukaryote organisms, viruses or virus-like organisms
11Water nucleophile; water bound by two Asp; all membrane-bound endopeptidases known only from eubacteria with active site on periplasmic side of cell membrane.
112222232219Water nucleophile; water bound by two Asp; all membrane-bound endopeptidases known only from eubacteria with active site on cytoplasmic side of cell membrane.
22212019112016161416175Cysteine nucleophile; catalytic residues in the order Cys, His, Asn (or Asp) in sequence
332322222223Cysteine nucleophile; catalytic residues in the order His, Cys in sequence
1221118Cysteine nucleophile; catalytic residues in the order His, Glu (or Asp), Cys in sequence
11111117Cysteine nucleophile; catalytic residues in the order Glu, Cys, His in sequence
1113Cysteine nucleophile; catalytic residues in the order His, Cys in sequence
222323223324Families of peptidase inhibitors not assigned to clans
11
11114
112
11
222623232125
11111122111Families of metallopeptidases not assigned to clans
6891013106681086Water nucleophile; water bound by single zinc ion ligated to two His (within the motif HEXXH) and Glu, His or Asp
11111117Water nucleophile; water bound by single zinc ion ligated to His, Glu (within the motif HXXE) and His
112138Water nucleophile; water bound by single zinc ion ligated to two His (within the motif HXXEH) and Glu
111111111110Water nucleophile; water bound by two zinc ions ligated by Lys, Asp, Asp, Asp, Glu
777877777771Water nucleophile; water bound by two cobalt or manganese ions ligated by Asp, Asp, His, Glu, Glu
8816131111131399111Water nucleophile; water bound by two zinc ions ligated by His (or Asp), Asp, Glu, Asp (or Glu), His
6614139101113108100Water nucleophile; water bound by two zinc ions ligated by His, His or Asp, Lys or Glu, His, His.
111111118Water nucleophile; water bound by single zinc ion ligated to two His (within the motif HEXXH) and Asp; membrane proteins with intramembrane active site.
465557656554Water nucleophile; water bound by single zinc ion ligated to two His and Asp (within the motif HSHP(X)9D)
112Asparagine nucleophile; catalytic residues in the order Asp, Asn in sequence; all self-processing endopeptidases
112Serine or cysteine nucleophile; catalytic residues in the order His, Asp, Ser (or Cys) in sequence; all endopeptidases
18191824191817192118191Threonine, serine or cysteine nucleophile at the N-terminus of mature enzyme
224432222326Serine or cysteine nucleophile; catalytic residues in the order Cys (or Ser), His, Glu in sequence.
334241114225Serine nucleophile; catalytic residues in the order Asp, His, Ser in sequence in family S8, but family S53 differs
444971105594752494333552Serine nucleophile; catalytic residues in the order Ser, Asp, His in sequence
228823443137Serine nucleophile; catalytic residues in the order Ser, Lys (within the motif SXXK) in sequence
334435335437Serine nucleophile; catalytic residues in the order Ser, Lys (or His) in sequence
112211222115Serine nucleophile; catalytic residues in the order Ser, His, Asp in sequence
224424331227Serine nucleophile; transmembrane protein with catalytic residues in the order Ser, His embedded in the membrane
111111111110
13121013111112121014118
11
2114
11
123