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Peptidases • Typhula sp. TRa3160C v1.0
Annotations/GenomesAmysub1Anoalb1Anobom1Anomyc1PleosPC15_2Plicr1Plucer1Ptegra1Radcon1TyphTRa3160C_1TotalAnnotation Description
Merops
2792493302783473263343814092623,195
30224127243825154013275Water nucleophile; water bound by two Asp from monomer or dimer; all endopeptidases, from eukaryote organisms, viruses or virus-like organisms
11Water nucleophile; water bound by two Asp; all membrane-bound endopeptidases known only from eubacteria with active site on periplasmic side of cell membrane.
122214111116Water nucleophile; water bound by two Asp; all membrane-bound endopeptidases known only from eubacteria with active site on cytoplasmic side of cell membrane.
112Water nucleophile; water bound by two Asp
12151616181914202916175Cysteine nucleophile; catalytic residues in the order Cys, His, Asn (or Asp) in sequence
344593674550Cysteine nucleophile; catalytic residues in the order His, Cys in sequence
1113112111Cysteine nucleophile; catalytic residues in the order His, Glu (or Asp), Cys in sequence
226223322327Families of peptidase inhibitors not assigned to clans
1113
1121321112
133463533637
22323231410243Families of metallopeptidases not assigned to clans
12121413322031541427229Water nucleophile; water bound by single zinc ion ligated to two His (within the motif HEXXH) and Glu, His or Asp
1151614Water nucleophile; water bound by single zinc ion ligated to His, Glu (within the motif HXXE) and His
121111211112Water nucleophile; water bound by single zinc ion ligated to two His (within the motif HXXEH) and Glu
111121119Water nucleophile; water bound by two zinc ions ligated by Lys, Asp, Asp, Asp, Glu
9796910899985Water nucleophile; water bound by two cobalt or manganese ions ligated by Asp, Asp, His, Glu, Glu
109108171916271318147Water nucleophile; water bound by two zinc ions ligated by His (or Asp), Asp, Glu, Asp (or Glu), His
1191417109109118108Water nucleophile; water bound by two zinc ions ligated by His, His or Asp, Lys or Glu, His, His.
111111118Water nucleophile; water bound by single zinc ion ligated to two His (within the motif HEXXH) and Asp; membrane proteins with intramembrane active site.
134Water nucleophile; water bound by single zinc ion ligated to two His and Asp (within the motifs HXXXD and HXH)
656565555553Water nucleophile; water bound by single zinc ion ligated to two His and Asp (within the motif HSHP(X)9D)
1214Asparagine nucleophile; catalytic residues in the order Asp, Asn in sequence; all self-processing endopeptidases
11Serine or cysteine nucleophile; catalytic residues in the order His, Asp, Ser (or Cys) in sequence; all endopeptidases
21202120202320212220208Threonine, serine or cysteine nucleophile at the N-terminus of mature enzyme
444586684655Serine or cysteine nucleophile; catalytic residues in the order Cys (or Ser), His, Glu in sequence.
111115Serine or threonine nucleophile; N-terminal nucleophile
1691712121116212512151Serine nucleophile; catalytic residues in the order Asp, His, Ser in sequence in family S8, but family S53 differs
11197127107127116108125183751,176Serine nucleophile; catalytic residues in the order Ser, Asp, His in sequence
111137953334Serine nucleophile; catalytic residues in the order Ser, Lys (within the motif SXXK) in sequence
324333333431Serine nucleophile; catalytic residues in the order Ser, Lys (or His) in sequence
66Serine nucleophile; catalytic residues in the order Ser, Lys in sequence
111111111110Serine nucleophile; catalytic residues in the order Ser, His, Asp in sequence
443442244435Serine nucleophile; transmembrane protein with catalytic residues in the order Ser, His embedded in the membrane
11Families of peptidases of unknown catalytic mechanism not assigned to clans
111111111110
11111812231222131010142
112
33