Peptidases • Lentinula raphanica INPA1820 v1.0
Annotations/GenomesLenafn1Lenafn_TMI1502_1Lened_B_1_1Lenedo1Lenlat1Lennov1Lenra_T_1Lenrap1Lenrap1_155LraINPA1820_1TotalAnnotation Description
Merops
3493373573343313303483453583553,444
34353030312937274235330Water nucleophile; water bound by two Asp from monomer or dimer; all endopeptidases, from eukaryote organisms, viruses or virus-like organisms
334333333331Water nucleophile; water bound by two Asp; all membrane-bound endopeptidases known only from eubacteria with active site on cytoplasmic side of cell membrane.
15161619161818171517167Cysteine nucleophile; catalytic residues in the order Cys, His, Asn (or Asp) in sequence
655556445550Cysteine nucleophile; catalytic residues in the order His, Cys in sequence
25311333627Cysteine nucleophile; catalytic residues in the order His, Glu (or Asp), Cys in sequence
99899812131310100Water nucleophile; water bound by Gln and Glu; all endopeptidases
9948109989984Families of peptidase inhibitors not assigned to clans
12111118
1111111119
434444344539
222222222220Families of metallopeptidases not assigned to clans
12121514111310111010118Water nucleophile; water bound by single zinc ion ligated to two His (within the motif HEXXH) and Glu, His or Asp
117111111116Water nucleophile; water bound by single zinc ion ligated to two His (within the motif HXXEH) and Glu
111111111110Water nucleophile; water bound by two zinc ions ligated by Lys, Asp, Asp, Asp, Glu
1099710101010111096Water nucleophile; water bound by two cobalt or manganese ions ligated by Asp, Asp, His, Glu, Glu
15141715151515151616153Water nucleophile; water bound by two zinc ions ligated by His (or Asp), Asp, Glu, Asp (or Glu), His
14142216151614161415156Water nucleophile; water bound by two zinc ions ligated by His, His or Asp, Lys or Glu, His, His.
111111111110Water nucleophile; water bound by single zinc ion ligated to two His (within the motif HEXXH) and Asp; membrane proteins with intramembrane active site.
311211110Water nucleophile; water bound by single zinc ion ligated to two His and Asp (within the motifs HXXXD and HXH)
878867556565Water nucleophile; water bound by single zinc ion ligated to two His and Asp (within the motif HSHP(X)9D)
27253027262625282627267Threonine, serine or cysteine nucleophile at the N-terminus of mature enzyme
674545665755Serine or cysteine nucleophile; catalytic residues in the order Cys (or Ser), His, Glu in sequence.
11Serine or threonine nucleophile; N-terminal nucleophile
13121311121215161415133Serine nucleophile; catalytic residues in the order Asp, His, Ser in sequence in family S8, but family S53 differs
1251171221171211151261261281281,225Serine nucleophile; catalytic residues in the order Ser, Asp, His in sequence
332333122224Serine nucleophile; catalytic residues in the order Ser, Lys (within the motif SXXK) in sequence
332222332325Serine nucleophile; catalytic residues in the order Ser, Lys (or His) in sequence
112Serine nucleophile; catalytic residues in the order Ser, Lys in sequence
111111121111Serine nucleophile; catalytic residues in the order Ser, His, Asp in sequence
11Serine nucleophile; catalytic residues in the order His, Ser within the motif HXS.
443444444439Serine nucleophile; transmembrane protein with catalytic residues in the order Ser, His embedded in the membrane
111111111110
16141815141315151614150
112