Peptidases • Pavlovales sp. CCMP2436 v1.0
Annotations/GenomesEmihu1Guith1Ochro2298_1Pavlov2436_1Pelago2097_1TotalAnnotation Description
Merops
6224894043163582,189
8653426Water nucleophile; water bound by two Asp from monomer or dimer; all endopeptidases, from eukaryote organisms, viruses or virus-like organisms
2444317Water nucleophile; water bound by two Asp; all membrane-bound endopeptidases known only from eubacteria with active site on cytoplasmic side of cell membrane.
5645463540222Cysteine nucleophile; catalytic residues in the order Cys, His, Asn (or Asp) in sequence
553215Cysteine nucleophile; catalytic residues in the order His, Cys in sequence
34173431Cysteine nucleophile; catalytic residues in the order His, Glu (or Asp), Cys in sequence
213Cysteine nucleophile; catalytic residues in the order Glu, Cys, His in sequence
112Cysteine nucleophile; catalytic residues in the order Cys, His, His in sequence
1531313Cysteine nucleophile; catalytic residues in the order His, Cys in sequence
6984835Families of peptidase inhibitors not assigned to clans
112
112
1214
11
11
112
22
11
11362224
22217
11
22
213
11136Families of metallopeptidases not assigned to clans
2940281710124Water nucleophile; water bound by single zinc ion ligated to two His (within the motif HEXXH) and Glu, His or Asp
81173130Water nucleophile; water bound by single zinc ion ligated to His, Glu (within the motif HXXE) and His
78108740Water nucleophile; water bound by single zinc ion ligated to two His (within the motif HXXEH) and Glu
4442418Water nucleophile; water bound by two zinc ions ligated by Lys, Asp, Asp, Asp, Glu
1110910848Water nucleophile; water bound by two cobalt or manganese ions ligated by Asp, Asp, His, Glu, Glu
910961448Water nucleophile; water bound by two zinc ions ligated by His (or Asp), Asp, Glu, Asp (or Glu), His
15976643Water nucleophile; water bound by two zinc ions ligated by His, His or Asp, Lys or Glu, His, His.
2259Water nucleophile; water bound by single zinc ion ligated to two His (within the motif HEXXH) and Asp; membrane proteins with intramembrane active site.
4645423Water nucleophile; water bound by single zinc ion ligated to two His and Asp (within the motif HSHP(X)9D)
11Water nucleophile; water bound by two cobalt ions ligated by Glu, Glu, His, His, Asp
11Water nucleophile; water bound by a metal ion but ligands unknown.
11Water nucleophile; water bound by single zinc ion ligated to Asp, His and His.
22239Asparagine nucleophile; catalytic residues in the order Asp, Asn in sequence; all self-processing endopeptidases
30856655Serine or cysteine nucleophile; catalytic residues in the order His, Asp, Ser (or Cys) in sequence; all endopeptidases
5026472434181Threonine, serine or cysteine nucleophile at the N-terminus of mature enzyme
158810849Serine or cysteine nucleophile; catalytic residues in the order Cys (or Ser), His, Glu in sequence.
66Cysteine nucleophile at the N-terminus of mature enzyme; catalytic residues in the order Cys, Thr, His
2215Serine or threonine nucleophile; N-terminal nucleophile
2171511458Serine nucleophile; catalytic residues in the order Asp, His, Ser in sequence in family S8, but family S53 differs
2131118410287597Serine nucleophile; catalytic residues in the order Ser, Asp, His in sequence
14352428Serine nucleophile; catalytic residues in the order Ser, Lys (within the motif SXXK) in sequence
10584532Serine nucleophile; catalytic residues in the order Ser, Lys (or His) in sequence
2114Serine nucleophile; catalytic residues in the order Ser, Lys in sequence
214111111195Serine nucleophile; catalytic residues in the order Ser, His, Asp in sequence
112Serine nucleophile; catalytic residues in the order His, Ser within the motif HXS.
91093940Serine nucleophile; transmembrane protein with catalytic residues in the order Ser, His embedded in the membrane
112Families of peptidases of unknown catalytic mechanism not assigned to clans
11
4468252060217