Peptidases • Vuilleminia comedens VcCUCC2015_SSI6 v1.0
Annotations/GenomesGlotr1_1Helsul1Jaaar1Neole1Punst1Thega1Vuicom1TotalAnnotation Description
Merops
3153313413203902784882,463
36335239491460283Water nucleophile; water bound by two Asp from monomer or dimer; all endopeptidases, from eukaryote organisms, viruses or virus-like organisms
111211310Water nucleophile; water bound by two Asp; all membrane-bound endopeptidases known only from eubacteria with active site on cytoplasmic side of cell membrane.
20191621161519126Cysteine nucleophile; catalytic residues in the order Cys, His, Asn (or Asp) in sequence
638545940Cysteine nucleophile; catalytic residues in the order His, Cys in sequence
111159Cysteine nucleophile; catalytic residues in the order His, Glu (or Asp), Cys in sequence
1121813Water nucleophile; water bound by Gln and Glu; all endopeptidases
333332320Families of peptidase inhibitors not assigned to clans
1113
1121117
232231316
333321217Families of metallopeptidases not assigned to clans
15152112152321122Water nucleophile; water bound by single zinc ion ligated to two His (within the motif HEXXH) and Glu, His or Asp
11111117Water nucleophile; water bound by single zinc ion ligated to two His (within the motif HXXEH) and Glu
11114Water nucleophile; water bound by two zinc ions ligated by Lys, Asp, Asp, Asp, Glu
981698121173Water nucleophile; water bound by two cobalt or manganese ions ligated by Asp, Asp, His, Glu, Glu
16181319191124120Water nucleophile; water bound by two zinc ions ligated by His (or Asp), Asp, Glu, Asp (or Glu), His
111911151191490Water nucleophile; water bound by two zinc ions ligated by His, His or Asp, Lys or Glu, His, His.
1111116Water nucleophile; water bound by single zinc ion ligated to two His (within the motif HEXXH) and Asp; membrane proteins with intramembrane active site.
666666642Water nucleophile; water bound by single zinc ion ligated to two His and Asp (within the motif HSHP(X)9D)
111115Asparagine nucleophile; catalytic residues in the order Asp, Asn in sequence; all self-processing endopeptidases
22Serine or cysteine nucleophile; catalytic residues in the order His, Asp, Ser (or Cys) in sequence; all endopeptidases
22222224212123155Threonine, serine or cysteine nucleophile at the N-terminus of mature enzyme
645465939Serine or cysteine nucleophile; catalytic residues in the order Cys (or Ser), His, Glu in sequence.
11Serine or threonine nucleophile; N-terminal nucleophile
11111610122729116Serine nucleophile; catalytic residues in the order Asp, His, Ser in sequence in family S8, but family S53 differs
1121289911614591187878Serine nucleophile; catalytic residues in the order Ser, Asp, His in sequence
489481447Serine nucleophile; catalytic residues in the order Ser, Lys (within the motif SXXK) in sequence
324333422Serine nucleophile; catalytic residues in the order Ser, Lys (or His) in sequence
11111117Serine nucleophile; catalytic residues in the order Ser, His, Asp in sequence
334234423Serine nucleophile; transmembrane protein with catalytic residues in the order Ser, His embedded in the membrane
11Families of peptidases of unknown catalytic mechanism not assigned to clans
11111117
1482212481920143
11
112
3216