Peptidases • Aspergillus campestris IBT 28561 v1.0
Annotations/GenomesAspcam1Aspfu1Aspni7Aspnid1Aspnov1Aspoch1Aspor1Aspste1TotalAnnotation Description
Merops
2662743882913222294143712,555
7415477131370Water nucleophile; water bound by two Asp from monomer or dimer; all endopeptidases, from eukaryote organisms, viruses or virus-like organisms
11412211Water nucleophile; water bound by two Asp; all membrane-bound endopeptidases known only from eubacteria with active site on periplasmic side of cell membrane.
41833296568Water nucleophile; water bound by two Asp; all membrane-bound endopeptidases known only from eubacteria with active site on cytoplasmic side of cell membrane.
2450341051193440262Cysteine nucleophile; catalytic residues in the order Cys, His, Asn (or Asp) in sequence
3333343325Cysteine nucleophile; catalytic residues in the order His, Cys in sequence
1111228Cysteine nucleophile; catalytic residues in the order His, Glu (or Asp), Cys in sequence
111115Cysteine nucleophile; catalytic residues in the order Glu, Cys, His in sequence
112Cysteine nucleophile; active peptidase is a homodimer with active site His and Glu from one monomer and Cys from the other. Catalytic residues in the order His, Glu, Cys in each monomer.
112Cysteine nucleophile; catalytic residues in the order Cys, His, His in sequence
2254233223Water nucleophile; water bound by Gln and Glu; all endopeptidases
11Water nucleophile; water bound by Glu; all self-cleaving endopeptidases
7755654544Families of peptidase inhibitors not assigned to clans
2114
11
11
121311211
124221113
11
111377188142098Families of metallopeptidases not assigned to clans
1313141615112512119Water nucleophile; water bound by single zinc ion ligated to two His (within the motif HEXXH) and Glu, His or Asp
11111229Water nucleophile; water bound by single zinc ion ligated to His, Glu (within the motif HXXE) and His
1113Water nucleophile; water bound by single zinc ion ligated to two His (within the motif HXXEH) and Glu
112Water nucleophile; water bound by two zinc ions ligated by Lys, Asp, Asp, Asp, Glu
10485637750Water nucleophile; water bound by two cobalt or manganese ions ligated by Asp, Asp, His, Glu, Glu
1717264025192630200Water nucleophile; water bound by two zinc ions ligated by His (or Asp), Asp, Glu, Asp (or Glu), His
9717885131481Water nucleophile; water bound by two zinc ions ligated by His, His or Asp, Lys or Glu, His, His.
11Water nucleophile; water bound by single zinc ion ligated to two His (within the motif HEXXH) and Asp; membrane proteins with intramembrane active site.
3351421322Water nucleophile; water bound by single zinc ion ligated to two His and Asp (within the motif HSHP(X)9D)
1113Water nucleophile; water bound by single zinc ion ligated to Asp, His and His.
11Asparagine nucleophile; catalytic residues in the order Asn, Glu in sequence; all self-processing endopeptidases
1214311Serine or cysteine nucleophile; catalytic residues in the order His, Asp, Ser (or Cys) in sequence; all endopeptidases
2120201722162620162Threonine, serine or cysteine nucleophile at the N-terminus of mature enzyme
6684729850Serine or cysteine nucleophile; catalytic residues in the order Cys (or Ser), His, Glu in sequence.
112Cysteine nucleophile at the N-terminus of mature enzyme; catalytic residues in the order Cys, Thr, His
11125Serine or threonine nucleophile; N-terminal nucleophile
11Families of serine peptidases not assigned to clans
58124749655Serine nucleophile; catalytic residues in the order Asp, His, Ser in sequence in family S8, but family S53 differs
7459160619468153131800Serine nucleophile; catalytic residues in the order Ser, Asp, His in sequence
1011016271047Serine nucleophile; catalytic residues in the order Ser, Lys (within the motif SXXK) in sequence
5331147428Serine nucleophile; catalytic residues in the order Ser, Lys (or His) in sequence
2522223220Serine nucleophile; catalytic residues in the order Ser, His, Asp in sequence
11Serine nucleophile; catalytic residues in the order Ser, Glu, His
2112211111Serine nucleophile; transmembrane protein with catalytic residues in the order Ser, His embedded in the membrane
22339423Families of peptidases of unknown catalytic mechanism not assigned to clans
111111118
91198139191290
11
1113
618385193796