Peptidases • Setomelanomma holmii CBS 110217 v1.0
Annotations/GenomesCocca1Coclu2Cocmi1Cocsa1Cucbe1Pyrtr1Setho1Stano2TotalAnnotation Description
Merops
3353413263303282974133432,713
2218212216132213147Water nucleophile; water bound by two Asp from monomer or dimer; all endopeptidases, from eukaryote organisms, viruses or virus-like organisms
10111010888772Water nucleophile; water bound by two Asp; all membrane-bound endopeptidases known only from eubacteria with active site on cytoplasmic side of cell membrane.
2621242728263425211Cysteine nucleophile; catalytic residues in the order Cys, His, Asn (or Asp) in sequence
4444444331Cysteine nucleophile; catalytic residues in the order His, Cys in sequence
111111118Cysteine nucleophile; catalytic residues in the order His, Glu (or Asp), Cys in sequence
1111211210Cysteine nucleophile; catalytic residues in the order Glu, Cys, His in sequence
111111118Cysteine nucleophile; catalytic residues in the order His, Cys in sequence
3133211115Water nucleophile; water bound by Gln and Glu; all endopeptidases
5555454437Families of peptidase inhibitors not assigned to clans
111112119
3232337528
5546424434Families of metallopeptidases not assigned to clans
1219131117142016122Water nucleophile; water bound by single zinc ion ligated to two His (within the motif HEXXH) and Glu, His or Asp
7777778757Water nucleophile; water bound by single zinc ion ligated to His, Glu (within the motif HXXE) and His
111112119Water nucleophile; water bound by single zinc ion ligated to two His (within the motif HXXEH) and Glu
6666669752Water nucleophile; water bound by two cobalt or manganese ions ligated by Asp, Asp, His, Glu, Glu
2323212124192522178Water nucleophile; water bound by two zinc ions ligated by His (or Asp), Asp, Glu, Asp (or Glu), His
10981181281177Water nucleophile; water bound by two zinc ions ligated by His, His or Asp, Lys or Glu, His, His.
11114Water nucleophile; water bound by single zinc ion ligated to two His and Asp (within the motifs HXXXD and HXH)
3433332324Water nucleophile; water bound by single zinc ion ligated to two His and Asp (within the motif HSHP(X)9D)
2222222317Serine or cysteine nucleophile; catalytic residues in the order His, Asp, Ser (or Cys) in sequence; all endopeptidases
2122212023192221169Threonine, serine or cysteine nucleophile at the N-terminus of mature enzyme
89988814872Serine or cysteine nucleophile; catalytic residues in the order Cys (or Ser), His, Glu in sequence.
112Cysteine nucleophile at the N-terminus of mature enzyme; catalytic residues in the order Cys, Thr, His
1111112210Serine or threonine nucleophile; N-terminal nucleophile
161313149131412104Serine nucleophile; catalytic residues in the order Asp, His, Ser in sequence in family S8, but family S53 differs
11412711811111797161133978Serine nucleophile; catalytic residues in the order Ser, Asp, His in sequence
76466610752Serine nucleophile; catalytic residues in the order Ser, Lys (within the motif SXXK) in sequence
3333223322Serine nucleophile; catalytic residues in the order Ser, Lys (or His) in sequence
1111222212Serine nucleophile; catalytic residues in the order Ser, His, Asp in sequence
3434534531Serine nucleophile; transmembrane protein with catalytic residues in the order Ser, His embedded in the membrane
1113Families of peptidases of unknown catalytic mechanism not assigned to clans
112
121011121011151091
11
2123122114