Peptidases • Emiliania huxleyi CCMP1516 v1.0
Annotations/GenomesEmihu1TotalAnnotation Description
Merops
622622
88Water nucleophile; water bound by two Asp from monomer or dimer; all endopeptidases, from eukaryote organisms, viruses or virus-like organisms
22Water nucleophile; water bound by two Asp; all membrane-bound endopeptidases known only from eubacteria with active site on cytoplasmic side of cell membrane.
5656Cysteine nucleophile; catalytic residues in the order Cys, His, Asn (or Asp) in sequence
55Cysteine nucleophile; catalytic residues in the order His, Cys in sequence
33Cysteine nucleophile; catalytic residues in the order His, Glu (or Asp), Cys in sequence
22Cysteine nucleophile; catalytic residues in the order Glu, Cys, His in sequence
11Cysteine nucleophile; catalytic residues in the order His, Cys in sequence
66Families of peptidase inhibitors not assigned to clans
11
11
11
11
11
22
22
11Families of metallopeptidases not assigned to clans
2929Water nucleophile; water bound by single zinc ion ligated to two His (within the motif HEXXH) and Glu, His or Asp
88Water nucleophile; water bound by single zinc ion ligated to His, Glu (within the motif HXXE) and His
77Water nucleophile; water bound by single zinc ion ligated to two His (within the motif HXXEH) and Glu
44Water nucleophile; water bound by two zinc ions ligated by Lys, Asp, Asp, Asp, Glu
1111Water nucleophile; water bound by two cobalt or manganese ions ligated by Asp, Asp, His, Glu, Glu
99Water nucleophile; water bound by two zinc ions ligated by His (or Asp), Asp, Glu, Asp (or Glu), His
1515Water nucleophile; water bound by two zinc ions ligated by His, His or Asp, Lys or Glu, His, His.
22Water nucleophile; water bound by single zinc ion ligated to two His (within the motif HEXXH) and Asp; membrane proteins with intramembrane active site.
44Water nucleophile; water bound by single zinc ion ligated to two His and Asp (within the motif HSHP(X)9D)
11Water nucleophile; water bound by single zinc ion ligated to Asp, His and His.
22Asparagine nucleophile; catalytic residues in the order Asp, Asn in sequence; all self-processing endopeptidases
3030Serine or cysteine nucleophile; catalytic residues in the order His, Asp, Ser (or Cys) in sequence; all endopeptidases
5050Threonine, serine or cysteine nucleophile at the N-terminus of mature enzyme
1515Serine or cysteine nucleophile; catalytic residues in the order Cys (or Ser), His, Glu in sequence.
66Cysteine nucleophile at the N-terminus of mature enzyme; catalytic residues in the order Cys, Thr, His
22Serine or threonine nucleophile; N-terminal nucleophile
2121Serine nucleophile; catalytic residues in the order Asp, His, Ser in sequence in family S8, but family S53 differs
213213Serine nucleophile; catalytic residues in the order Ser, Asp, His in sequence
1414Serine nucleophile; catalytic residues in the order Ser, Lys (within the motif SXXK) in sequence
1010Serine nucleophile; catalytic residues in the order Ser, Lys (or His) in sequence
2121Serine nucleophile; catalytic residues in the order Ser, His, Asp in sequence
11Serine nucleophile; catalytic residues in the order His, Ser within the motif HXS.
99Serine nucleophile; transmembrane protein with catalytic residues in the order Ser, His embedded in the membrane
11Families of peptidases of unknown catalytic mechanism not assigned to clans
4444