Peptidases • Thamnidium elegans v1.0
Annotations/GenomesBacci1Hesve2finisherSCLichy1Morel2Mucci2Parpar1Phybl2Rhimi1_1Synrac1Thaele1Umbra1TotalAnnotation Description
Merops
4222833114053042652842532832942723,376
3126253624192820202322274Water nucleophile; water bound by two Asp from monomer or dimer; all endopeptidases, from eukaryote organisms, viruses or virus-like organisms
11Water nucleophile; water bound by two Asp; all membrane-bound endopeptidases known only from eubacteria with active site on periplasmic side of cell membrane.
10635434444350Water nucleophile; water bound by two Asp; all membrane-bound endopeptidases known only from eubacteria with active site on cytoplasmic side of cell membrane.
4027352535302929313424339Cysteine nucleophile; catalytic residues in the order Cys, His, Asn (or Asp) in sequence
6457657666260Cysteine nucleophile; catalytic residues in the order His, Cys in sequence
16313223224240Cysteine nucleophile; catalytic residues in the order His, Glu (or Asp), Cys in sequence
1113Cysteine nucleophile; catalytic residues in the order Glu, Cys, His in sequence
11211111211Cysteine nucleophile; catalytic residues in the order Cys, His, His in sequence
221112112114Cysteine nucleophile; catalytic residues in the order His, Cys in sequence
9578776767675Families of peptidase inhibitors not assigned to clans
112
1111116
1113
11
121228
1211111231115
5231231142125
1111111111111Families of metallopeptidases not assigned to clans
2612162823201718152622223Water nucleophile; water bound by single zinc ion ligated to two His (within the motif HEXXH) and Glu, His or Asp
426Water nucleophile; water bound by single zinc ion ligated to His, Glu (within the motif HXXE) and His
32117Water nucleophile; water bound by single zinc ion ligated to two His (within the motif HXXEH) and Glu
4353443444341Water nucleophile; water bound by two zinc ions ligated by Lys, Asp, Asp, Asp, Glu
1511111013121214111211132Water nucleophile; water bound by two cobalt or manganese ions ligated by Asp, Asp, His, Glu, Glu
1611171311101511141017145Water nucleophile; water bound by two zinc ions ligated by His (or Asp), Asp, Glu, Asp (or Glu), His
1187712796871092Water nucleophile; water bound by two zinc ions ligated by His, His or Asp, Lys or Glu, His, His.
111121111212Water nucleophile; water bound by single zinc ion ligated to two His (within the motif HEXXH) and Asp; membrane proteins with intramembrane active site.
7333655636249Water nucleophile; water bound by single zinc ion ligated to two His and Asp (within the motif HSHP(X)9D)
3223131112322Serine or cysteine nucleophile; catalytic residues in the order His, Asp, Ser (or Cys) in sequence; all endopeptidases
3521202023211717202018232Threonine, serine or cysteine nucleophile at the N-terminus of mature enzyme
4356333324339Serine or cysteine nucleophile; catalytic residues in the order Cys (or Ser), His, Glu in sequence.
11114Serine or threonine nucleophile; N-terminal nucleophile
227151910111911111110146Serine nucleophile; catalytic residues in the order Asp, His, Ser in sequence in family S8, but family S53 differs
9680829567615546766771796Serine nucleophile; catalytic residues in the order Ser, Asp, His in sequence
12318111128Serine nucleophile; catalytic residues in the order Ser, Lys (within the motif SXXK) in sequence
7445574637355Serine nucleophile; catalytic residues in the order Ser, Lys (or His) in sequence
33Serine nucleophile; catalytic residues in the order Ser, Lys in sequence
2211313111218Serine nucleophile; catalytic residues in the order Ser, His, Asp in sequence
11964747675470Serine nucleophile; transmembrane protein with catalytic residues in the order Ser, His embedded in the membrane
112Families of peptidases of unknown catalytic mechanism not assigned to clans
211111111111
2623237024202624232017296
11
1111116
11
11